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https://hdl.handle.net/20.500.14279/23611
Τίτλος: | AM-FM texture image analysis in multiple sclerosis brain white matter lesions |
Συγγραφείς: | Loizou, Christos P. Murray, Víctor Pattichis, Marios S. Pantziaris, Marios Seimenis, Ioannis Pattichis, Constantinos S. |
Major Field of Science: | Engineering and Technology |
Field Category: | Medical Engineering |
Λέξεις-κλειδιά: | Multiple sclerosis;AM-FM analysis;Brain white matter;Disease progression |
Ημερομηνία Έκδοσης: | Μαΐ-2010 |
Πηγή: | 12th Mediterranean Conference on Medical and Biological Engineering and Computing, 2010, 27-30 May, Chalkidiki, Greece |
Start page: | 446 |
End page: | 449 |
Περιοδικό: | Mediterranean Conference on Medical and Biological Engineering and Computing |
Περίληψη: | In this study we investigate the use of multiscale Amplitude Modulation-Frequency Modulation (AM-FM) methods for analyzing brain white matter lesions that are associated with multiple sclerosis MRI lesions imaged at 0 and 6-12 months. We use the instantaneous amplitude (IA) and the instantaneous frequency (IF) to assess disease progression. The IA and the IF were calculated in transverse sections of T2- weighted magnetic resonance (MR) images acquired from 38 symptomatic untreated subjects between the first and the second examination scan. The findings suggest that the high-, medium-, and low- frequency scale instantaneous amplitude and frequency can be used to differentiate between normal tissue and lesions at 0 and 6-12 months. Moreover, support vector machine (SVM) models gave satisfactory results for differentiating lesions at 0 months using the medium scale IA and IF components for expanded disability status scale (EDSS) <=2 and EDSS >2. Further work is needed with more subjects in validating the proposed AM-FM analysis. © 2010 International Federation for Medical and Biological Engineering. |
URI: | https://hdl.handle.net/20.500.14279/23611 |
ISBN: | 978-3-642-13039-7 |
DOI: | 10.1007/978-3-642-13039-7_112 |
Rights: | © Springer |
Type: | Conference Papers |
Affiliation: | Intercollege University of New Mexico Cyprus Institute of Neurology and Genetics Ayios Therissos Medical Diagnostic Center University of Cyprus |
Publication Type: | Peer Reviewed |
Εμφανίζεται στις συλλογές: | Δημοσιεύσεις σε συνέδρια /Conference papers or poster or presentation |
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