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https://hdl.handle.net/20.500.14279/9518| Τίτλος: | Optimization of a horizontal slot waveguide biosensor to detect DNA hybridization | Συγγραφείς: | Viphavakit, Charusluk Komodromos, Michael Themistos, Christos Mohammed, Waleed S. Kalli, Kyriacos Rahman, B. M. Azizur |
Major Field of Science: | Engineering and Technology | Field Category: | Electrical Engineering - Electronic Engineering - Information Engineering | Λέξεις-κλειδιά: | DNA;DNA, Single-Stranded;Equipment design;Models theoretical;Oxides;Oxygen;Refractometry;Reproducibility of results;Silicon;Silicon dioxide;Biosensing techniques;Nucleic Acid Hybridization | Ημερομηνία Έκδοσης: | 20-Μαΐ-2015 | Πηγή: | Applied Optics, 2015, vol. 54, no. 15, pp. 4881-4888. | Volume: | 54 | Issue: | 15 | Start page: | 4881 | End page: | 4888 | DOI: | 10.1364/AO.54.004881 | Περιοδικό: | Applied Optics | Περίληψη: | A full-vectorial H-field formulation-based finite element approach is used to optimize a biosensor structure incorporating a horizontal slot waveguide. It is designed to detect DNA hybridization through the change of the effective index of the waveguide structure. The key parameters, such as normalized power confinement, power density, change in effective index, and sensitivity are presented by optimizing the device parameters of the slot waveguide. It is shown here that a 90.0 μm long compact Mach-Zehnder section can be designed with horizontal slot waveguide to detect DNA hybridization and for a ring resonator arrangement a sensitivity of 893.5 nm/RIU is obtained. | URI: | https://hdl.handle.net/20.500.14279/9518 | ISSN: | 1559128X | DOI: | 10.1364/AO.54.004881 | Rights: | © Optical Society of America. | Type: | Article | Affiliation: | Frederick University Bangkok University Cyprus University of Technology City, University of London |
Publication Type: | Peer Reviewed |
| Εμφανίζεται στις συλλογές: | Άρθρα/Articles |
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