Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14279/9518| Title: | Optimization of a horizontal slot waveguide biosensor to detect DNA hybridization | Authors: | Viphavakit, Charusluk Komodromos, Michael Themistos, Christos Mohammed, Waleed S. Kalli, Kyriacos Rahman, B. M. Azizur |
Major Field of Science: | Engineering and Technology | Field Category: | Electrical Engineering - Electronic Engineering - Information Engineering | Keywords: | DNA;DNA, Single-Stranded;Equipment design;Models theoretical;Oxides;Oxygen;Refractometry;Reproducibility of results;Silicon;Silicon dioxide;Biosensing techniques;Nucleic Acid Hybridization | Issue Date: | 20-May-2015 | Source: | Applied Optics, 2015, vol. 54, no. 15, pp. 4881-4888. | Volume: | 54 | Issue: | 15 | Start page: | 4881 | End page: | 4888 | DOI: | 10.1364/AO.54.004881 | Journal: | Applied Optics | Abstract: | A full-vectorial H-field formulation-based finite element approach is used to optimize a biosensor structure incorporating a horizontal slot waveguide. It is designed to detect DNA hybridization through the change of the effective index of the waveguide structure. The key parameters, such as normalized power confinement, power density, change in effective index, and sensitivity are presented by optimizing the device parameters of the slot waveguide. It is shown here that a 90.0 μm long compact Mach-Zehnder section can be designed with horizontal slot waveguide to detect DNA hybridization and for a ring resonator arrangement a sensitivity of 893.5 nm/RIU is obtained. | URI: | https://hdl.handle.net/20.500.14279/9518 | ISSN: | 1559128X | DOI: | 10.1364/AO.54.004881 | Rights: | © Optical Society of America. | Type: | Article | Affiliation : | Frederick University Bangkok University Cyprus University of Technology City, University of London |
Publication Type: | Peer Reviewed |
| Appears in Collections: | Άρθρα/Articles |
CORE Recommender
SCOPUSTM
Citations
42
checked on Nov 9, 2023
WEB OF SCIENCETM
Citations
37
Last Week
0
0
Last month
0
0
checked on Oct 29, 2023
Page view(s) 50
410
Last Week
0
0
Last month
2
2
checked on Dec 3, 2024
Google ScholarTM
Check
Altmetric
Items in KTISIS are protected by copyright, with all rights reserved, unless otherwise indicated.