Παρακαλώ χρησιμοποιήστε αυτό το αναγνωριστικό για να παραπέμψετε ή να δημιουργήσετε σύνδεσμο προς αυτό το τεκμήριο:
https://hdl.handle.net/20.500.14279/9451
Τίτλος: | Association between urinary levels of bisphenol A and its monochlorinated derivative and obesity | Συγγραφείς: | Andra, Syam S. Makris, Konstantinos C. |
Major Field of Science: | Medical and Health Sciences | Field Category: | Other Medical Sciences | Λέξεις-κλειδιά: | Biomarker;Bisphenol A;Body mass index;Exposure;Monochlorinated bisphenol A;Obesity | Ημερομηνία Έκδοσης: | 20-Ιου-2015 | Πηγή: | Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering, vol. 50, no. 11, pp. 1169-1179. | Volume: | 50 | Issue: | 11 | Start page: | 1169 | End page: | 1179 | DOI: | 10.1080/10934529.2015.1047674 | Περιοδικό: | Journal of Environmental Science and Health, Part A: Toxic/Hazardous Substances and Environmental Engineering | Περίληψη: | Population-based studies suggest the association between exposures to bisphenol A (BPA) and obesity. However, no human studies are available that link exposures to chlorinated derivatives of BPA with obesity biomarkers. The objective of this exploratory post hoc analysis of our cross-sectional study's dataset was to evaluate the association between urinary levels of BPA and monochlorinated BPA (mono-ClBPA) with body mass index (BMI) in a random sample of 223 adults (≥18 years) from the general population in Cyprus. Univariate analysis and multiple logistic regressions were performed for descriptive statistics and estimating odds ratio (OR) of above normal BMI, respectively. We observed a relatively weak positive association between urinary mono-ClBPA and BMI, such as (i) 76 ng g-1 in participants with above normal BMI (≥25 kg m-2) versus 55 ng g-1 in those with normal BMI (<25 kg m-2) (P for mean difference = 0.053) and (ii) higher percentage of participants with above normal BMI in the high urinary mono-ClBPA tertile (63% in tertile 3 and 57% in tertile 2 versus 50% in tertile 1, P for trend = 0.056). Similar tests of association between urinary BPA and BMI showed null outcome. A dichotomously-classified group analysis showed an increased odds ratio (OR) for higher BMI in the group with high creatinine-adjusted urinary levels of BPA and mono-ClBPA when compared with the participants group with low levels for both compounds [logistic model adjusted for gender and health status as potential confounders; adjusted OR (95% CI): 2.34 (1.10, 5.10), P = 0.027]. Measurements of both BPA and its trace chlorinated derivative in human matrices may be warranted for a comprehensive exposure assessment towards improving our understanding of their obesogenic effects. | URI: | https://hdl.handle.net/20.500.14279/9451 | ISSN: | 10934529 | DOI: | 10.1080/10934529.2015.1047674 | Rights: | © Taylor & Francis Group | Type: | Article | Affiliation: | Cyprus University of Technology | Publication Type: | Peer Reviewed |
Εμφανίζεται στις συλλογές: | Άρθρα/Articles |
CORE Recommender
SCOPUSTM
Citations
21
checked on 9 Νοε 2023
WEB OF SCIENCETM
Citations
20
19
Last Week
1
1
Last month
1
1
checked on 29 Οκτ 2023
Page view(s)
442
Last Week
0
0
Last month
6
6
checked on 25 Δεκ 2024
Google ScholarTM
Check
Altmetric
Όλα τα τεκμήρια του δικτυακού τόπου προστατεύονται από πνευματικά δικαιώματα