Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14279/9451
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Andra, Syam S. | - |
dc.contributor.author | Makris, Konstantinos C. | - |
dc.date.accessioned | 2017-02-03T12:19:42Z | - |
dc.date.available | 2017-02-03T12:19:42Z | - |
dc.date.issued | 2015-07-20 | - |
dc.identifier.citation | Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering, vol. 50, no. 11, pp. 1169-1179. | en_US |
dc.identifier.issn | 10934529 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.14279/9451 | - |
dc.description.abstract | Population-based studies suggest the association between exposures to bisphenol A (BPA) and obesity. However, no human studies are available that link exposures to chlorinated derivatives of BPA with obesity biomarkers. The objective of this exploratory post hoc analysis of our cross-sectional study's dataset was to evaluate the association between urinary levels of BPA and monochlorinated BPA (mono-ClBPA) with body mass index (BMI) in a random sample of 223 adults (≥18 years) from the general population in Cyprus. Univariate analysis and multiple logistic regressions were performed for descriptive statistics and estimating odds ratio (OR) of above normal BMI, respectively. We observed a relatively weak positive association between urinary mono-ClBPA and BMI, such as (i) 76 ng g-1 in participants with above normal BMI (≥25 kg m-2) versus 55 ng g-1 in those with normal BMI (<25 kg m-2) (P for mean difference = 0.053) and (ii) higher percentage of participants with above normal BMI in the high urinary mono-ClBPA tertile (63% in tertile 3 and 57% in tertile 2 versus 50% in tertile 1, P for trend = 0.056). Similar tests of association between urinary BPA and BMI showed null outcome. A dichotomously-classified group analysis showed an increased odds ratio (OR) for higher BMI in the group with high creatinine-adjusted urinary levels of BPA and mono-ClBPA when compared with the participants group with low levels for both compounds [logistic model adjusted for gender and health status as potential confounders; adjusted OR (95% CI): 2.34 (1.10, 5.10), P = 0.027]. Measurements of both BPA and its trace chlorinated derivative in human matrices may be warranted for a comprehensive exposure assessment towards improving our understanding of their obesogenic effects. | en_US |
dc.format | en_US | |
dc.language.iso | en | en_US |
dc.relation.ispartof | Journal of Environmental Science and Health, Part A: Toxic/Hazardous Substances and Environmental Engineering | en_US |
dc.rights | © Taylor & Francis Group | en_US |
dc.subject | Biomarker | en_US |
dc.subject | Bisphenol A | en_US |
dc.subject | Body mass index | en_US |
dc.subject | Exposure | en_US |
dc.subject | Monochlorinated bisphenol A | en_US |
dc.subject | Obesity | en_US |
dc.title | Association between urinary levels of bisphenol A and its monochlorinated derivative and obesity | en_US |
dc.type | Article | en_US |
dc.doi | 10.1080/10934529.2015.1047674 | en_US |
dc.collaboration | Cyprus University of Technology | en_US |
dc.subject.category | Other Medical Sciences | en_US |
dc.journals | Subscription | en_US |
dc.country | Cyprus | en_US |
dc.subject.field | Medical and Health Sciences | en_US |
dc.publication | Peer Reviewed | en_US |
dc.identifier.doi | 10.1080/10934529.2015.1047674 | en_US |
dc.relation.issue | 11 | en_US |
dc.relation.volume | 50 | en_US |
cut.common.academicyear | 2014-2015 | en_US |
dc.identifier.spage | 1169 | en_US |
dc.identifier.epage | 1179 | en_US |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
crisitem.author.dept | Department of Rehabilitation Sciences | - |
crisitem.author.faculty | Faculty of Health Sciences | - |
crisitem.author.orcid | 0000-0001-5251-8619 | - |
crisitem.author.parentorg | Faculty of Health Sciences | - |
Appears in Collections: | Άρθρα/Articles |
CORE Recommender
SCOPUSTM
Citations
21
checked on Nov 9, 2023
WEB OF SCIENCETM
Citations
20
19
Last Week
1
1
Last month
1
1
checked on Oct 29, 2023
Page view(s)
442
Last Week
0
0
Last month
6
6
checked on Dec 25, 2024
Google ScholarTM
Check
Altmetric
Items in KTISIS are protected by copyright, with all rights reserved, unless otherwise indicated.