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  4. An in vitro Model for Experimental Evaluation of Sonothrombolysis under Tissue-mimicking Material Conditions
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An in vitro Model for Experimental Evaluation of Sonothrombolysis under Tissue-mimicking Material Conditions

Journal
Journal of Medical Ultrasound
Date Issued
2023
Author(s)
Drakos, Theocharis  
Evripidou, Georgios  
Damianou, Christakis A.  
DOI
10.4103/jmu.jmu_52_22
Abstract
The mechanical properties of therapeutic ultrasound (US) have attracted scientific interest for thrombolysis enhancement in combination with thrombolytic agents and microbubbles (MBs). The aim of the study was to develop an in vitro model to observe how the effects of sonothrombolysis change in the case where a tissue-mimicking material (TMM) is placed in the path of the US beam before the clot.
Subjects

tissue-mimicking mate...

Focused ultrasound

microbubbles

stroke

thrombolytic agentc

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