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https://hdl.handle.net/20.500.14279/29637| Title: | Circulating sex hormone binding globulin levels are modified with intensive lifestyle intervention, but their changes did not independently predict diabetes risk in the Diabetes Prevention Program | Authors: | Aroda, Vanita R Christophi, Costas A. Edelstein, Sharon L Perreault, Leigh Kim, Catherine Golden, Sherita H Horton, Edward Mather, Kieren J |
Major Field of Science: | Medical and Health Sciences | Field Category: | Health Sciences | Keywords: | diabetes mellitus;hormone;life style;primary prevention;type 2 | Issue Date: | 16-Dec-2020 | Source: | BMJ Open Diabetes Research and Care, 2020, vol. 8, iss. 2 | Volume: | 8 | Issue: | 2 | Journal: | BMJ open diabetes research & care | Abstract: | Sex hormone binding globulin (SHBG) levels are reported to be inversely associated with diabetes risk. It is unknown whether diabetes prevention interventions increase SHBG and whether resultant changes in SHBG affect diabetes risk. The purpose of this analysis was to determine whether intensive lifestyle intervention (ILS) or metformin changed circulating SHBG and if resultant changes influenced diabetes risk in the Diabetes Prevention Program (DPP). | URI: | https://hdl.handle.net/20.500.14279/29637 | ISSN: | 20524897 | DOI: | 10.1136/bmjdrc-2020-001841 | Rights: | © Author(s) Attribution-NonCommercial-NoDerivatives 4.0 International |
Type: | Article | Affiliation : | MedStar Health Research Institute Harvard Medical School George Washington University University of Colorado University of Michigan The Johns Hopkins University School of Medicine Joslin Diabetes Center Indiana University School of Medicine |
| Appears in Collections: | Άρθρα/Articles |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| christophi costas.pdf | Full text | 761.15 kB | Adobe PDF | View/Open |
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