Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/29637
Title: Circulating sex hormone binding globulin levels are modified with intensive lifestyle intervention, but their changes did not independently predict diabetes risk in the Diabetes Prevention Program
Authors: Aroda, Vanita R 
Christophi, Costas A. 
Edelstein, Sharon L 
Perreault, Leigh 
Kim, Catherine 
Golden, Sherita H 
Horton, Edward 
Mather, Kieren J 
Major Field of Science: Medical and Health Sciences
Field Category: Health Sciences
Keywords: diabetes mellitus;hormone;life style;primary prevention;type 2
Issue Date: 16-Dec-2020
Source: BMJ Open Diabetes Research and Care, 2020, vol. 8, iss. 2
Volume: 8
Issue: 2
Journal: BMJ open diabetes research & care 
Abstract: Sex hormone binding globulin (SHBG) levels are reported to be inversely associated with diabetes risk. It is unknown whether diabetes prevention interventions increase SHBG and whether resultant changes in SHBG affect diabetes risk. The purpose of this analysis was to determine whether intensive lifestyle intervention (ILS) or metformin changed circulating SHBG and if resultant changes influenced diabetes risk in the Diabetes Prevention Program (DPP).
URI: https://hdl.handle.net/20.500.14279/29637
ISSN: 20524897
DOI: 10.1136/bmjdrc-2020-001841
Rights: © Author(s)
Attribution-NonCommercial-NoDerivatives 4.0 International
Type: Article
Affiliation : MedStar Health Research Institute 
Harvard Medical School 
George Washington University 
University of Colorado 
University of Michigan 
The Johns Hopkins University School of Medicine 
Joslin Diabetes Center 
Indiana University School of Medicine 
Appears in Collections:Άρθρα/Articles

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