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https://hdl.handle.net/20.500.14279/22883
Τίτλος: | Carotid Ultrasound Boundary Study (CUBS): An Open Multicenter Analysis of Computerized Intima-Media Thickness Measurement Systems and Their Clinical Impact | Συγγραφείς: | Meiburger, Kristen M. Zahnd, Guillaume Faita, Francesco Loizou, Christos P. Carvalho, Catarina Steinman, David A. Gibello, Lorenzo Bruno, Rosa Maria Marzola, Francesco Clarenbach, Ricarda Francesconi, Martina Nicolaides, Andrew N. Campilho, Aurelio Ghotbi, Reza Kyriacou, Efthyvoulos C. Navab, Nassir Griffin, Maura Panayiotou, Andrie G. Gherardini, Rachele Varetto, Gianfranco Bianchini, Elisabetta Pattichis, Constantinos S. Ghiadoni, Lorenzo Rouco, José Molinari, Filippo |
Major Field of Science: | Medical and Health Sciences | Field Category: | Clinical Medicine | Λέξεις-κλειδιά: | Atherosclerosis;Cardiovascular events;Carotid artery intima–media thickness;Open-source database;Segmentation;Ultrasound imaging | Ημερομηνία Έκδοσης: | Αυγ-2021 | Πηγή: | Ultrasound in Medicine and Biology, vol. 47, no. 8, pp. 2442-2455 | Volume: | 47 | Issue: | 8 | Start page: | 2442 | End page: | 2455 | Περιοδικό: | Ultrasound in Medicine and Biology | Περίληψη: | Common carotid intima-media thickness (CIMT) is a commonly used marker for atherosclerosis and is often computed in carotid ultrasound images. An analysis of different computerized techniques for CIMT measurement and their clinical impacts on the same patient data set is lacking. Here we compared and assessed five computerized CIMT algorithms against three expert analysts' manual measurements on a data set of 1088 patients from two centers. Inter- and intra-observer variability was assessed, and the computerized CIMT values were compared with those manually obtained. The CIMT measurements were used to assess the correlation with clinical parameters, cardiovascular event prediction through a generalized linear model and the Kaplan-Meier hazard ratio. CIMT measurements obtained with a skilled analyst's segmentation and the computerized segmentation were comparable in statistical analyses, suggesting they can be used interchangeably for CIMT quantification and clinical outcome investigation. To facilitate future studies, the entire data set used is made publicly available for the community at http://dx.doi.org/10.17632/fpv535fss7.1. | URI: | https://hdl.handle.net/20.500.14279/22883 | ISSN: | 03015629 | DOI: | 10.1016/j.ultrasmedbio.2021.03.022 | Rights: | This is an open access article under the CC BY-NC-ND license | Type: | Article | Affiliation: | Politecnico di Torino Technische Universität München CNR - National Research Council of Italy University of Cyprus INESC University of Toronto University of Torino University of Pisa Paris Cardiovascular Research Centre Université de Paris Helios Klinikum München West Cyprus Cardiovascular Disease and Educational Research Trust University of Porto Frederick University Johns Hopkins University Vascular Screening and Diagnostic Centre Cyprus University of Technology University of Cyprus Research Center of Information and Communication Technologies University of A Coruña |
Publication Type: | Peer Reviewed |
Εμφανίζεται στις συλλογές: | Άρθρα/Articles |
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1-s2.0-S0301562921001411-main.pdf | Fulltext | 2.68 MB | Adobe PDF | Δείτε/ Ανοίξτε |
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