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https://hdl.handle.net/20.500.14279/1948
Title: | Serum CA 125 combined with transvaginal ultrasonography for ovarian cancer screening | Authors: | Roupa, Zoi Faros, Efthimios Tzavelas, George Kotrotsiou, Evangelia Sotiropoulou, Penelope Karanikola, Evridiki Skifta, Evdoxia Ardavanis, Alexandros S. Raftopoulos, Vasilios |
metadata.dc.contributor.other: | Ραφτόπουλος, Βασίλειος | Major Field of Science: | Medical and Health Sciences | Field Category: | MEDICAL AND HEALTH SCIENCES | Keywords: | Serum CA 125;Ultrasonography;Cancer | Issue Date: | Dec-2004 | Source: | In Vivo, 2004, vol.18, no.6, pp. 831-836 | Volume: | 18 | Issue: | 6 | Start page: | 831 | End page: | 836 | Journal: | In Vivo | Abstract: | Background: The aim of this study was to evaluate the combination of serum CA125 and Transvaginal Ultra Sonography (TVUS) score, as a screening procedure for ovarian cancer in premenopausal and postmenopausal women. Patients and Methods: A retrospective case-control pilot study was conducted. The files of 120 women with ovarian neoplasia detected by TVUS and increased CA125 level, within the framework of a prevention program, were reviewed. The relationship between the above tests and epithelial malignancy was investigated using the SPSS-12 program for Windows. Results: The combination of CA125 value exceeding 30U/ml and a TVUS score ≥35 had a sensitivity of 81.7% and specificity of 100% in predicting ovarian cancer. Mathematical analysis of the logistic model of our variables revealed a mathematical model that can calculate the likelihood of ovarian cancer detection, by using a combination of CA125≥30U/ml and TVUS score≥35. Conclusion: By combining TVUS and CA125, an accurate prediction for the presence of ovarian cancer may be achieved. Further investigation in a larger population is warranted. | URI: | https://hdl.handle.net/20.500.14279/1948 | ISSN: | 17917549 | Rights: | © International Institute of Anticancer Research | Type: | Article | Affiliation : | University of Thessaly | Publication Type: | Peer Reviewed |
Appears in Collections: | Άρθρα/Articles |
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