Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14279/19415
Title: | Focused ultrasound robotic system for very small bore magnetic resonance imaging | Authors: | Damianou, Christakis A. Giannakou, Marinos Evripidou, Nikolas Kegel, Stefan Huber, Peter E. Jenne, J̈urgen Walter |
Major Field of Science: | Engineering and Technology | Field Category: | Medical Engineering | Keywords: | HIFU;MRgFUS;MRI;Positioning;Robotic system | Issue Date: | Dec-2020 | Source: | The International Journal of Medical Robotics and Computer Assisted Surgery, 2020, vol. 16, no. 6, pp. 1-9 | Volume: | 16 | Issue: | 6 | Start page: | 1 | End page: | 9 | Journal: | The International Journal of Medical Robotics and Computer Assisted Surgery | Abstract: | Background: A magnetic resonance imaging (MRI) compatible robotic system for focused ultrasound was developed for small animal like mice or rats that fits into a 9.4 T MRI scanner (Bruker Biospec 9420, Bruker Biospin, Ettlingen, Germany). The robotic system includes two computer-controlled linear stages. Materials and Methods: The robotic system was evaluated in a mouse-shaped, real-size agar-based mimicking material, which has similar acoustical properties as soft tissues. The agar content was 6% weight per volume (w/v), 4% w/v silica while the rest was degassed water. The transducer used has a diameter of 4 cm, operates with 2.6 MHz and focuses energy at 5 cm. Results: The MRI compatibility of the robotic system was evaluated in a 9.4 T small animal scanner. The efficacy of the ultrasonic transducer was evaluated in the mimicking material using temperature measurements. Conclusions: The proposed robotic system can be utilized in a 9.4 T small animal MRI scanner. The proposed system is functional, compact and simple thus providing a useful tool for preclinical research in mice and rats. | URI: | https://hdl.handle.net/20.500.14279/19415 | ISSN: | 1478596X | DOI: | 10.1002/rcs.2165 | Rights: | © The Authors. This is an open access article under the terms of the Creative Commons Attribution License. | Type: | Article | Affiliation : | Cyprus University of Technology Medsonic Ltd German Cancer Research Center MEDIRI GmbH |
Publication Type: | Peer Reviewed |
Appears in Collections: | Άρθρα/Articles |
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Robotics Computer Surgery - 2020 - Damianou - Focused ultrasound robotic system for very small bore magnetic resonance.pdf | Fulltext | 1.38 MB | Adobe PDF | View/Open |
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