Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/19415
Title: Focused ultrasound robotic system for very small bore magnetic resonance imaging
Authors: Damianou, Christakis A. 
Giannakou, Marinos 
Evripidou, Nikolas 
Kegel, Stefan 
Huber, Peter E. 
Jenne, J̈urgen Walter 
Major Field of Science: Engineering and Technology
Field Category: Medical Engineering
Keywords: HIFU;MRgFUS;MRI;Positioning;Robotic system
Issue Date: Dec-2020
Source: The International Journal of Medical Robotics and Computer Assisted Surgery, 2020, vol. 16, no. 6, pp. 1-9
Volume: 16
Issue: 6
Start page: 1
End page: 9
Journal: The International Journal of Medical Robotics and Computer Assisted Surgery 
Abstract: Background: A magnetic resonance imaging (MRI) compatible robotic system for focused ultrasound was developed for small animal like mice or rats that fits into a 9.4 T MRI scanner (Bruker Biospec 9420, Bruker Biospin, Ettlingen, Germany). The robotic system includes two computer-controlled linear stages. Materials and Methods: The robotic system was evaluated in a mouse-shaped, real-size agar-based mimicking material, which has similar acoustical properties as soft tissues. The agar content was 6% weight per volume (w/v), 4% w/v silica while the rest was degassed water. The transducer used has a diameter of 4 cm, operates with 2.6 MHz and focuses energy at 5 cm. Results: The MRI compatibility of the robotic system was evaluated in a 9.4 T small animal scanner. The efficacy of the ultrasonic transducer was evaluated in the mimicking material using temperature measurements. Conclusions: The proposed robotic system can be utilized in a 9.4 T small animal MRI scanner. The proposed system is functional, compact and simple thus providing a useful tool for preclinical research in mice and rats.
URI: https://hdl.handle.net/20.500.14279/19415
ISSN: 1478596X
DOI: 10.1002/rcs.2165
Rights: © The Authors. This is an open access article under the terms of the Creative Commons Attribution License.
Type: Article
Affiliation : Cyprus University of Technology 
Medsonic Ltd 
German Cancer Research Center 
MEDIRI GmbH 
Publication Type: Peer Reviewed
Appears in Collections:Άρθρα/Articles

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This item is licensed under a Creative Commons License Creative Commons