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https://hdl.handle.net/20.500.14279/19375
Τίτλος: | Magnetic Resonance Imaging–Guided Focused Ultrasound Positioning System for Preclinical Studies in Small Animals | Συγγραφείς: | Drakos, Theoharis Giannakou, Marinos Menikou, Georgios Damianou, Christakis A. |
Major Field of Science: | Engineering and Technology | Field Category: | Medical Engineering | Λέξεις-κλειδιά: | Magnetic resonance imaging;Mouse;Positioning;Ultrasound | Ημερομηνία Έκδοσης: | Ιου-2021 | Πηγή: | Journal of Ultrasound in Medicine, 2021, vol. 40, no. 7, pp. 1343-1352 | Volume: | 40 | Issue: | 7 | Start page: | 1343 | End page: | 1352 | Περιοδικό: | Journal of Ultrasound in Medicine | Περίληψη: | Objectives: A positioning device compatible with magnetic resonance imaging (MRI) used for preclinical studies in small animals was developed that fits in MRI scanners up to 7 T. The positioning device was designed with two computer-controlled linear stages. Methods: The positioning device was evaluated in an agar-based phantom, which mimics soft tissues, and in a rabbit. Experiments with this positioning device were performed in an MRI system using the agar-based phantom. The transducer used had a diameter of 50 mm, operated at 0.5 MHz, and focused energy at 60 mm. Results: Magnetic resonance thermometry was used to assess the functionality of the device, which showed adequate deposition of thermal energy and sufficient positional accuracy in all axes. Conclusions: The proposed system fits in MRI scanners up to 7 T. Because of the size of the positioning device, at the moment, it can be used to perform preclinical studies on small animals such as mice, rats, and rabbits. | URI: | https://hdl.handle.net/20.500.14279/19375 | ISSN: | 15509613 | DOI: | 10.1002/jum.15514 | Rights: | © The Authors | Type: | Article | Affiliation: | Medsonic Ltd Cyprus University of Technology |
Publication Type: | Peer Reviewed |
Εμφανίζεται στις συλλογές: | Άρθρα/Articles |
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jum.15514.pdf | Fulltext | 4 MB | Adobe PDF | Δείτε/ Ανοίξτε |
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