Haemodialysis adequacy – contemporary trends
Journal
Health Science Journal
Date Issued
2009
Author(s)
Abstract
Haemodialysis constitutes a prescribed clinical action, a fact which leads us to the search of
indexes that control the adequacy of haemodialysis and to a more precise estimation of the
intended and the performed result.
Objective: The purpose of this literature review was to present the quantitative and
mathematical indexes used for the calculation of the haemodialysis adequacy in the daily
clinical practice.
Method and material: The method οf this study included bibliography research from both the
review and the research literature which carried out mainly internationally over the last years
and referred to haemodialysis adequacy.
Results: In daily clinical practice, useful tools for the calculation of haemodialysis adequacy are
the indexes Urea Reduction Rate (URR), single-pool Kt/V (spKt/V) index, equilibrated Kt/V
(eKt/V) index and weekly standard Kt/V (std Kt/V) index. The knowledge of factors that
influence the urea clearance within treatment and can offer important help to the successful
haemodialysis prescription, are: blood flow, filter permeability, haemodialysis dialysate flow and
recirculation.
Clinical indexes are may also be considered for a more effective haemodialysis process: good
natural health, good regulation of arterial pressure, good regulation of liquids balance and
absence of clinical points or uraemia symptoms.
Conclusions: The main conclusion of the present review is to apply the indexes in daily clinical
practice. Moreover, it is important to set out certain proposals for further research, so that the
health professionals improve not only the clinical practice but also the theoretical approach in
the field of determination and estimation of haemodialysis adequacy.
indexes that control the adequacy of haemodialysis and to a more precise estimation of the
intended and the performed result.
Objective: The purpose of this literature review was to present the quantitative and
mathematical indexes used for the calculation of the haemodialysis adequacy in the daily
clinical practice.
Method and material: The method οf this study included bibliography research from both the
review and the research literature which carried out mainly internationally over the last years
and referred to haemodialysis adequacy.
Results: In daily clinical practice, useful tools for the calculation of haemodialysis adequacy are
the indexes Urea Reduction Rate (URR), single-pool Kt/V (spKt/V) index, equilibrated Kt/V
(eKt/V) index and weekly standard Kt/V (std Kt/V) index. The knowledge of factors that
influence the urea clearance within treatment and can offer important help to the successful
haemodialysis prescription, are: blood flow, filter permeability, haemodialysis dialysate flow and
recirculation.
Clinical indexes are may also be considered for a more effective haemodialysis process: good
natural health, good regulation of arterial pressure, good regulation of liquids balance and
absence of clinical points or uraemia symptoms.
Conclusions: The main conclusion of the present review is to apply the indexes in daily clinical
practice. Moreover, it is important to set out certain proposals for further research, so that the
health professionals improve not only the clinical practice but also the theoretical approach in
the field of determination and estimation of haemodialysis adequacy.