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Τίτλος: Manual and automated intima-media thickness and diameter measurements of the common carotid artery in patients with renal failure disease
Συγγραφείς: Loizou,  Christos P. 
Kasparis, Takis 
Lazarou, Theodoros 
Pattichis, Constantinos S. 
Pantziaris, Marios 
Major Field of Science: Engineering and Technology
Field Category: Medical Engineering
Λέξεις-κλειδιά: Carotid diameter;Common carotid artery;Intima-media thickness;Renal failure disease;Segmentation;Ultrasound imaging
Ημερομηνία Έκδοσης: 1-Οκτ-2014
Πηγή: Computers in Biology and Medicine, 2014, vol. 53, pp. 220-229
Volume: 53
Start page: 220
End page: 229
Περιοδικό: Computers in Biology and Medicine 
Περίληψη: The objective of this study was to investigate differences in intima-media thickness (IMT) and diameter (D) measurements of the common carotid artery (CCA) in ultrasound imaging in normal subjects and renal failure disease (RFD) patients. Manual measurements by two experts and automated segmentation measurements (based on snakes and active contour models (ACM)) were carried out on 73 normal subjects, and 80 RFD patients. Statistical analysis was carried out using the Wilcoxon rank-sum test at p<0.05. Results demonstrated that the mean IMT and D measurements were significantly higher for the RFD group versus the normal group. Moreover, there was no significant difference between the manual and automated measurements. The ACM segmentation was slightly more accurate than segmentation based on snakes. Further work is needed to validate these findings on a larger group of subjects.
URI: https://hdl.handle.net/20.500.14279/9586
ISSN: 00104825
DOI: 10.1016/j.compbiomed.2014.08.003
Rights: © Elsevier
Type: Article
Affiliation: Intercollege 
Cyprus University of Technology 
Limassol General Hospital 
University of Cyprus 
Cyprus Institute of Neurology and Genetics 
Publication Type: Peer Reviewed
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