Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14279/8867
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Pericleous, S. | - |
dc.contributor.author | Mathieson, W. | - |
dc.contributor.author | Middleton, Nicos | - |
dc.contributor.author | McKay, S. | - |
dc.contributor.author | Biswas, A. | - |
dc.contributor.author | Thomas, G. | - |
dc.contributor.author | Spalding, D. | - |
dc.contributor.author | Hutchins, R. | - |
dc.date.accessioned | 2016-09-01T09:49:38Z | - |
dc.date.available | 2016-09-01T09:49:38Z | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | HPB, 2011, vol. 13, supp. 2, pp. 30-31 | en_US |
dc.identifier.issn | 1365182X | - |
dc.identifier.uri | https://hdl.handle.net/20.500.14279/8867 | - |
dc.description.abstract | Cholangiocarcinoma (CC) is an uncommon disease with a dismal prognosis. Patients with surgically unresectable disease benefi t little from conventional anticancer therapies such as chemotherapy and radiotherapy. 1-(2-chlorophenylN-methylpropyl)-3-isoquinolinecarboxamide (PK11195) is a benzodiazepine receptor ligand which antagonizes Bcl-2 and Bcl-XL function thus preventing the inhibition of apoptosis. Our aim was to determine the effect of adding PK11195 in vitro to commercially available chemotherapy agents on cultured CC cell lines. | en_US |
dc.format | en_US | |
dc.language.iso | en | en_US |
dc.relation.ispartof | HPB | en_US |
dc.rights | © International Hepato-Pancreato-Biliary Association | en_US |
dc.subject | Cholangiocarcinoma | en_US |
dc.subject | Chemotherapy | en_US |
dc.title | PK11195, a peripheral benzodiazepine receptor ligand, potentiates cytotoxic action on cholangiocarcinoma cell lines | en_US |
dc.type | Article | en_US |
dc.collaboration | Imperial College London | en_US |
dc.collaboration | Royal London Hospital | en_US |
dc.collaboration | Cyprus University of Technology | en_US |
dc.subject.category | Health Sciences | en_US |
dc.journals | Subscription | en_US |
dc.country | Cyprus | en_US |
dc.subject.field | Medical and Health Sciences | en_US |
dc.publication | Peer Reviewed | en_US |
dc.identifier.doi | 10.1111/j.1477-2574.2011.00308.x | en_US |
dc.identifier.pmid | 21457418 | - |
dc.dept.handle | 123456789/118 | en |
dc.relation.issue | 2 | en_US |
dc.relation.volume | 13 | en_US |
cut.common.academicyear | 2010-2011 | en_US |
dc.identifier.spage | 30 | en_US |
dc.identifier.epage | 31 | en_US |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
crisitem.journal.journalissn | 1365-182X | - |
crisitem.journal.publisher | Elsevier | - |
crisitem.author.dept | Department of Nursing | - |
crisitem.author.faculty | Faculty of Health Sciences | - |
crisitem.author.orcid | 0000-0001-6358-8591 | - |
crisitem.author.parentorg | Faculty of Health Sciences | - |
Appears in Collections: | Άρθρα/Articles |
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