Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/8867
DC FieldValueLanguage
dc.contributor.authorPericleous, S.-
dc.contributor.authorMathieson, W.-
dc.contributor.authorMiddleton, Nicos-
dc.contributor.authorMcKay, S.-
dc.contributor.authorBiswas, A.-
dc.contributor.authorThomas, G.-
dc.contributor.authorSpalding, D.-
dc.contributor.authorHutchins, R.-
dc.date.accessioned2016-09-01T09:49:38Z-
dc.date.available2016-09-01T09:49:38Z-
dc.date.issued2011-
dc.identifier.citationHPB, 2011, vol. 13, supp. 2, pp. 30-31en_US
dc.identifier.issn1365182X-
dc.identifier.urihttps://hdl.handle.net/20.500.14279/8867-
dc.description.abstractCholangiocarcinoma (CC) is an uncommon disease with a dismal prognosis. Patients with surgically unresectable disease benefi t little from conventional anticancer therapies such as chemotherapy and radiotherapy. 1-(2-chlorophenylN-methylpropyl)-3-isoquinolinecarboxamide (PK11195) is a benzodiazepine receptor ligand which antagonizes Bcl-2 and Bcl-XL function thus preventing the inhibition of apoptosis. Our aim was to determine the effect of adding PK11195 in vitro to commercially available chemotherapy agents on cultured CC cell lines.en_US
dc.formatpdfen_US
dc.language.isoenen_US
dc.relation.ispartofHPBen_US
dc.rights© International Hepato-Pancreato-Biliary Associationen_US
dc.subjectCholangiocarcinomaen_US
dc.subjectChemotherapyen_US
dc.titlePK11195, a peripheral benzodiazepine receptor ligand, potentiates cytotoxic action on cholangiocarcinoma cell linesen_US
dc.typeArticleen_US
dc.collaborationImperial College Londonen_US
dc.collaborationRoyal London Hospitalen_US
dc.collaborationCyprus University of Technologyen_US
dc.subject.categoryHealth Sciencesen_US
dc.journalsSubscriptionen_US
dc.countryCyprusen_US
dc.subject.fieldMedical and Health Sciencesen_US
dc.publicationPeer Revieweden_US
dc.identifier.doi10.1111/j.1477-2574.2011.00308.xen_US
dc.identifier.pmid21457418-
dc.dept.handle123456789/118en
dc.relation.issue2en_US
dc.relation.volume13en_US
cut.common.academicyear2010-2011en_US
dc.identifier.spage30en_US
dc.identifier.epage31en_US
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypearticle-
crisitem.journal.journalissn1365-182X-
crisitem.journal.publisherElsevier-
crisitem.author.deptDepartment of Nursing-
crisitem.author.facultyFaculty of Health Sciences-
crisitem.author.orcid0000-0001-6358-8591-
crisitem.author.parentorgFaculty of Health Sciences-
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