Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14279/14877
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kiparissides, Alexandros | - |
dc.contributor.author | Koutinas, Michalis | - |
dc.contributor.author | Kontoravdi, Cleo | - |
dc.contributor.author | Mantalaris, Athanasios A. | - |
dc.contributor.author | Pistikopoulos, Efstratios N. | - |
dc.date.accessioned | 2019-08-07T10:53:17Z | - |
dc.date.available | 2019-08-07T10:53:17Z | - |
dc.date.issued | 2011-06 | - |
dc.identifier.citation | Automatica, 2011, vol. 47, no. 6, pp. 1147-1155 | en_US |
dc.identifier.issn | 00051098 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.14279/14877 | - |
dc.description.abstract | This work presents a holistic 'closed loop' approach for the development of models of biological systems. The ever-increasing availability of experimental information necessitates the advancement of a systematic methodology to organise and utilise these data. Herein, we present a biological model building framework that maps the treatment of the information from the initial conception of the model, through its experimental validation and finally to its application in model-based optimisation studies. We highlight and discuss current issues associated with the development of mathematical models of biological systems and share our perspective towards a holistic 'closed loop' approach that will facilitate the control of the in vitro through the in silico. | en_US |
dc.format | en_US | |
dc.language.iso | en | en_US |
dc.relation.ispartof | Automatica | en_US |
dc.rights | © Elsevier | en_US |
dc.subject | Model analysis | en_US |
dc.subject | Biological systems model development | en_US |
dc.subject | Sensitivity analysis | en_US |
dc.subject | Design of experiments | en_US |
dc.title | 'Closing the loop' in biological systems modeling-from the in silico to the in vitro | en_US |
dc.type | Article | en_US |
dc.collaboration | Imperial College London | en_US |
dc.collaboration | Cyprus University of Technology | en_US |
dc.subject.category | Biological Sciences | en_US |
dc.journals | Subscription | en_US |
dc.country | United Kingdom | en_US |
dc.country | Cyprus | en_US |
dc.subject.field | Natural Sciences | en_US |
dc.publication | Peer Reviewed | en_US |
dc.identifier.doi | 10.1016/j.automatica.2011.01.013 | en_US |
dc.relation.issue | 6 | en_US |
dc.relation.volume | 47 | en_US |
cut.common.academicyear | 2010-2011 | en_US |
dc.identifier.spage | 1147 | en_US |
dc.identifier.epage | 1155 | en_US |
item.openairetype | article | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
crisitem.author.dept | Department of Chemical Engineering | - |
crisitem.author.faculty | Faculty of Geotechnical Sciences and Environmental Management | - |
crisitem.author.orcid | 0000-0002-5371-4280 | - |
crisitem.author.parentorg | Faculty of Geotechnical Sciences and Environmental Management | - |
crisitem.journal.journalissn | 0005-1098 | - |
crisitem.journal.publisher | Elsevier | - |
Appears in Collections: | Άρθρα/Articles |
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