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https://hdl.handle.net/20.500.14279/14042| Title: | Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study | Authors: | Menditto, Enrica Costa, Elísio Midão, Luis Bosnic-Anticevich, Sinthia Novellino, Ettore Bialek, Slawomir Briedis, Vitalis Mair, Alpana Rajabian-Soderlund, Rojin Arnavielhe, Sylvie Bedbrook, Anna Magnan, Antoine O. Mahboub, Bassam Hassan Saleh Hassan Maier, D. Majer, Ivan Mandajieva, E. Morais-Almeida, Mário A. Manning, Peter J. De Manuel-Keenoy, Esteban Marshall, Gailen D. Braido, Fulvio Durham, Stephen R. Masjedi, Mohammad Reza Maspero, J.F. Mathieu-Dupas, E. Matta Campos, J.J. Matos, A.L. Maurer, Marcus Mavale-Manuel, Sandra Pereira, Ana Maria Mayora, O. Medina-Avalos, M.A. Du Toit, George L. Brightling, Christopher Edward E. Melo-Gomes, Elisabete Meltzer, E.O. Mercier, Jacques G. Miculinić, Neven Mihǎlţan, Florin Dumitru Milenković, Branislava A. Moda, Giuliana Mogica-Martinez, M.D. Todo-Bom, Ana Maria Dykewicz, Mark S. Mohammad, Y. Czarlewski, Wienczyslawa Momas, Isabelle Montefort, Stephen R. Monti, R. Mora Bogado, D. Morato-Castro, F.F. Mota-Pinto, A. Moura Santo, P. Münter, L. El-Gamal, Yehia M. Muraro, A. Kvedariene, Violeta Brozek, Jan L. Murray, Ruth Naclerio, Robert M. Nadif, Rachel Nalin, Marco Napoli, L. Namazova-Baranova, Leyla Seymurovna Neffen, Hugo E. Eklund, Patrik E. Niedeberger, V. Nekam, Kristof Neou, Angelos Bucca, Caterina Valiulis, Arunas Nieto, A. Nogueira-Silva, L. Nogues, Michel Nyembue, Tshipukane Dieudonné Odzhakova, C. Ėmužytė, Regina Ohta, Ken Okamoto, Yoshitaka Okubo, Kimihiro Onorato, G. L. Buhl, Roland Ortega Cisneros, M. Bergmann, Karl Christian Ouedraogo, Solange Pali-Schöll, Isabella Palkonen, Susanna Farrell, J. Panzner, Petr Park, Hae Sim Papi, Alberto Passalacqua, Giovanni G. Paulino, E. Buonaiuto, Roland Pawankar, Ruby U. Pedersen, Soøren Erik Klimek, Ludger Pépin, J. L. Farsi, A. Persico, M. Phillips, J. Picard, Robert Pigearias, Bernard Pin, Isabelle Pitsios, C. Panaitescu, C. Plavec, Davor Pohl, Wolfgang Popov, T. A. Ferreira de Mello Jr, J. Mösges, Ralph Portejoie, Fabienne Potter, Paul C. Pozzi, A.C. Price, David B. Puy, Robert Pugin, B. Burguete Cabañas, María Teresa Pulido Ross, R.E. Przemecka, M. Larenas-Linnemann, Désirée E.S. Rabe, Klaus Friedrich Raciborski, Filip Pfaar, Oliver Ribeirinho, I. Rimmer, J. Rivero-Yeverino, D. Rizzo, J.A. Rizzo, M.C. Burte, Emilie Robalo-Cordeiro, Carlos Bocheńska-Marciniak, Małgorzata Ródenas Rigla, Francisco Rodo, X. Rodriguez Gonzalez, M. Rodriguez-Mañas, Leocadio Zuberbier, Torsten Rolland, Christine Rodrigues Valle, S. Román-Rodrνguez, Miguel Romano, Antonino Bush, Andrew P. Ferrero, J. Rodriguez-Zagal, E Rolla, G. Romano, M. Rosado-Pinto, José E. Rosário, Nélson Augusto Rottem, Menachem Cardona, Victoria Sagara, H. Salimäki, J. Sańchez-Borges, Mario Fink-Wagner, Antje H. Caballero-Fonseca, Fernán Sastre-Dominguez, J. Scadding, Glenis Kathleen Schunemann, H.J. Scichilone, Nicola Schmid-Grendelmeier, Peter D. Serpa, F. S. Shamai, S. Mullol, Joaquim Sierra, M. Fiocchi, Alessandro Simons, F. Estelle R. Caillaud, Denis Siroux, V. Sisul, Juan Carlos Skrindo, Ingebjørg Solé, Dirceu Somekh, David Sondermann, M. Sooronbaev, Talantbek M. Sova, M. Forti, S. Papadopoulos, Nikos G. Sorensen, M. Annesi-Maesano, Isabella Sorlini, M. Spranger, Otto Stelmach, Rafael Stukas, R. Sunyer, J. Strozek, J. Szylling, A. Fuentes Perez, M. Tebyriçá, J.N. Thibaudon, M. Prokopakis, Emmanuel P Caimmi, Davide Paolo To, T. Todo Bom, A. Trama, U. Triggiani, Massimo Suppli Ulrik, C. Urrutia-Pereira, M. Gálvez-Romero, J.L. Valenta, Rudolf Valero, Antonio Luνs Valovirta, Erkka Juhani van Eerd, M. Calderõn, Moiśes A. Bewick, Michael Van-Ganse, Éric H. van Hague, M. VandenPlas, Olivier Ventura, M. T. Gamkrelidze, Amiran G. Vezzani, Giorgio Vasankari, Tuula M. Vatrella, A. Verissimo, M.T. Viart, F. Camargos, Paulo Augusto Moreira Viegi, Giovanni Ryan, Dermot P. Vicheva, D. Vontetsianos, Theodore Garcia-Aymerich, J. Wagenmann, Martin Walker, Samantha M. Wallace, D. V. Wang, De Yun Waserman, S. Werfel, T. Camuzat, Thierry Westman, M. Williams, Dennis M. Roller-Wirnsberger, Regina E García-Cobas, C.Y. Williams, Siân Wilson, Nicola M. Wright, John P. Wroczynski, P. Yakovliev, P. Yawn, Barbara P. Yiallouros, Panayiotis K. Canfora, G. Yorgancioglu, Arzu Arzu Yusuf, Osman Mohammad Garcia-Cruz, M.H. Zar, Heather J. Tomazic, Peter Valentin Zhang, Luo Zhong, Nanshan Zernotti, Mario Emilio Zhanat, I. Zidarn, Mihaela Zuberbier, Thorsten Canonica, Giorgio Walter Zubrinich, C. Bogus-Buczynska, Izabela Zurkuhlen, A. Cruz, Alvaro A Kuna, Piotr B. Samolinski, Boleslaw Fokkens, Wytske J Reitsma, Sietze Bosse, Isabelle Fontaine, Jean-François Laune, Daniel Carlsen, Kai Håkon Cecchi, Lorenzo Haahtela, Tari M.K. Toppila-Salmi, Sanna Bachert, Claus Hellings, Peter W Melén, Erik Wickman, Magnus Bindslev-Jensen, Carsten Eller, Esben O'Hehir, Robyn E. Cingi, Cemal Gemıcıoğlu, Bilun Carreiro-Martins, Pedro Gemıcıoğlu, Bilun Kalaycì, Ömer Ivancevich, Juan Carlos Bousquet, Jean J. Aberer, Werner Agache, Ioana O. Akdiş, Cezmi A. Akdiş, Mübeccel Aliberti, M. R. Genova, S. Almeida, Rute Carriazo, A.M. Amat, Flore Angles, Rosana Ansotegui, Ignacio Javier Arnavielle, S. Asayag, Estrella Asarnoj, A. Arshad, Syed Hasan Avolio, Francesca Christoff, G Bacci, E. Baiardini, Ilaria Carr, Warner W. Bárbara, Cristina Barbagallo, Mario Baroni, Ilaria Barreto, Bruno Acatauassú Paes Basagana, Xavier Bateman, Eric D. Bedolla-Barajas, Martin Gereda, José E. Beghι, Bianca Bel, Elisabeth H.D. Bennoor, Kazi Saifuddin Antó, Josep María Benson, Mikael Bertorello, Lorenzo Białoszewski, Artur Z. Bieber, Thomas Bjermer, Leif H. Blain, Hubert Gerth van Wijk, R. Blasi, Francesco B. Blua, A. Cartier, C. Casale, Thomas B. Castellano, G. Cepeda, A.M. Chavannes, Niels H. Chen, Y. Chiron, Raphaël Chivato, Tomás Gomez, R.M. Chkhartishvili, Ekaterine Chuchalin, A. G. Devillier, Philippe Chung, K. F. Ciaravolo, M.M. Ciceran, A. Ciprandi, Giorgio Carvalho Coehlo, A.C. Colas, L. Colgan, E. Gómez-Vera, J. Coll, J. Conforti, D. Correia De Sousa, Jaime De Vries, Govert Cortés-Grimaldo, R.M. Corti, F. Costa-Dominguez, M.C. Courbis, A.L. Cox, L. Crescenzo, M. González-Dνaz, Sandra Čustović, Adnan Dahlen, S.E. D'Amato, G Dario, C. Keil, Thomas da Silva, J. Dauvilliers, Y. Darsow, Ulf De Blay, Frédéric De Carlo, Giuseppe Gotua, Maia A. Dedeu, Tony de Fátima Emerson, M. De Martino, B. Motta Rubina, NP Deleanu, Diana Sheikh, Aziz Demoly, Pascal Denburg, Judah A. Devillier, Philippe H Di Capua Ercolano, S. Boner, Attillio Loris Di Carluccio, N. Didier, Alain P. Dokić, Dejan Dominguez-Silva, M.G. Douagui, Habib B. Dray, Gérard Orlando, Valentina Dubakiene, Ruta Grisle, Ineta De Feo, Giulia Guidacci, M. Guldemond, N.A. Gϋtter, Zdenĕk Guzmán, María Antonieta Hajjam, J. Hernández, L. Hourihane, J.O'B. Huerta Villabolos, Y .R. Bonini, Matteo Humbert, Marc Iaccarino, Guido Illario, M Ispayeva, Z Jares, Edgardo José Jassem, E. Johnston, Sebastian Lennox Joos, Guy F.P. Jung, Ki Suck Just, Jocelyne Bonini, Sergio Jutel, Marek Kaidashev, I. Kalyoncu, Ali Fuat Stellato, Cristiana Karjalainen, J. Kardas, Przemysław Keith, Paul Kevin Khaitov, Musa R. Khaltaev, Nikolaο G. Kleine-Tebbe, J. Bouchard, Jacques Kowalski, Marek Leszek Kuitunen, M. Kull, Inger Kupczyk, M. Fonseca, João Almeida Krzych-Fałta, E. Lacwik, P. Lauri, D. Lavrut, J. Le, L.T.T. Boulet, Louis Philippe Lessa, M. Levato, G. Li, Jing Lieberman, Phil L. Lipiec, A. Malva, João Oliveira O. Lipworth, Brian Jonathon Lodrup Carlsen, K. C. Louis, Renaud E. Lourenço, O. Bourret, Rodolphe A. Luna-Pech, J.A. |
Major Field of Science: | Medical and Health Sciences | Field Category: | Health Sciences | Keywords: | Adherence;MHealth;Mobile technology;Observational study;Rhinitis;Treatment | Issue Date: | Apr-2019 | Source: | Clinical and Experimental Allergy, 2019, vol. 49, no. 4, pp. 442-460 | Volume: | 49 | Issue: | 4 | Start page: | 442 | End page: | 460 | Journal: | Clinical and Experimental Allergy | Abstract: | Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting. | ISSN: | 30597673 | DOI: | 10.1111/cea.13333 | Rights: | © Wiley | Type: | Article | Affiliation : | Iuliu Hatieganu University of Medicine and Pharmacy Lithuanian University of Health Sciences Academic Medical Centre Ain Shams University Ajou University Allergology unit, UHATEM “NIPirogov Allergy & Asthma Center Westend Allergy and Asthma Associates of Southern California Andalusian Agency for Healthcare Quality ARADyAL Spanish Research Network UiT The Arctic University of Norway University of Manchester University of Manitoba University of Medicine and Pharmacy Victor Babes University of Miami Dept of Medicine University of Milan Celentano pharmacy University of Minho University of Modena and Reggio Emilia University of Naples Federico II International Primary Care Respiratory Group IPCRG Sotiria Hospital University of North Carolina at Chapel Hill University of Oslo University of Palermo University of Parana University of Porto University of Salerno University of São Paulo Medical School Center for Rhinology and Allergology University of South Florida University of Southeast Bahia Specialist social worker IQ4U Consultants Ltd University of Southern Denmark University of Sydney University of Tennessee College of Medicine University of Torino & Mauriziano Hospital University of Toronto University of Turku University of Valencia University of Verona Hospital Center of Tuberculosis and Lung Diseases Tampere University Hospital University of Wuerzburg Argentina Center for Allergy and Immunology University of Zurich University‐Sorbonne Paris Cité Unversité Montpellier Uppsala University USL Toscana Centro Vilnius University Warsaw Medical University WHO GARD Planning Group Technische Universität München Wroclaw Medical University Centre for Research in Environmental Epidemiology (CREAL) Iranian Anti Tobacco Association Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle Centre Hospitalier Valenciennes Centre Hospitalo-Universitaire de Béni-Messous Centro Hospitalar de Lisboa Central Centro Hospitalar Sao Joao Centro Medico Docente la Trinidad Centro Medico Nacional Siglo XXI Telbios SRL Chairman of the Council of Municipality of Salerno Charité-Universitätsmedizin Berlin Charles University in Prague ISGlobal Chiba University Hospital Christian Albrechts University CHU et université d’Auvergne CHU Sart‐Tilman, and GIGA I3 research group CIBER Epidemiología y Salud Pública (CIBERESP) Clinica Ricardo Palma Tesorera de la SLAAI Clinica Santa Isabel Cofaser Comprehensive Allergy Center, Berlin Institute of Health CRI-Clinical Research International-Ltd Istanbul University Croatian Pulmonary Society CUF Descobertas Hospital CUF-Porto Hospital and Institute Cyprus University of Technology Danish Committee for Health Education Bambino Gesù Children's Research Hospital Holy See David Hide Asthma and Allergy Research Centre David Tvildiani Medical University DG for Health and Social Care Die Hautambulanz and Rothhaar study center Site de Référence de l'EIP on AHA CNR - National Research Council of Italy Emek Medical Center Erasmus University Medical Center Eskisehir Osmangazi University Euforea First Affiliated Hospital of Guangzhou Medical University European Academy of Paediatrics EFA European Federation of Allergy and Airways Diseases Patients' Associations European Health Futures Forum (EHFF) European Regional and Local Health Association Faculdade de Medicina de Lisboa Faculty of Medicine Universiti Teknologi MARA Johns Hopkins School of Medicine Farmacie Dei Golfi Group Federal District Base Hospital Institute Federal University of Bahia University of Mississippi Medical Center Federal University of Minas Gerais Federal University of Santa Catarina Federal University of the State of Rio de Janeiro Federazione Italiana Medici di MedicinaGenerale Federico II University Hospital GARD Chairman Georgian Association of Allergology and Clinical Immunology Karolinska Institutet Getafe University Hospital Ghent University Hospital Autonomous University of Baja California Global Allergy and Asthma Patient Platform Hacettepe University Hacettepe University School of Medicine Hallym University College of Medicine Hannover Medical School Heidelberg University Hietzing Hospital Hopital Foch Karolinska University Hospital Hôpital Gui‐de‐Chauliac Montpellier Hospital San Bernardo Salta Hospital Angeles del Carmen Hospital Angeles Pedregal Hospital City of Health and Science of Torino Hospital Civil de Guadalajara Dr Juan I Menchaca Hospital Del Mar Research Institute (IMIM) Hospital General Regional 1 “Dr Carlos Mc Gregor Sanchez Navarro” IMSS Hospital of the Hospitaller Brothers in Buda Hospital Quirón Bizkaia Hospital Regional del ISSSTE ‘Lic. López Mateos’ Kazakh National Medical University Thracian University King's College London Kronikgune Argentine Association of Respiratory Medicine KU Leuven KYomed INNOV Kyrgyzstan National Centre of Cardiology and Internal medicine Laboratory of Molecular immunology LANUA International Healthcare Consultancy Laval University Leiden University Medical Center Tishreen University School of Medicine Lithuanian University of Health Sciences MACVIA-France Maputo Central Hospital Argentine Federation of Otorhinolaryngology Societies McMaster University Médica Sur Clinical Foundation and Hospital Medical center “Research expert” Medical center Iskar Ltd Sofia Medical Consulting Czarlewski Medical Faculty Skopje Tokyo National Hospital Medical School Saint Antoine Medical University of Gdansk Medical University of Graz Medical University of Lodz Argentine Society of Allergy and Immunopathology Medical University of Vienna Medical University of Warsaw Medical University, Plovdiv Medicine University of Malta Metropolitan University Hospital Transilvania University of Brasov Monash University Montpellier University Hospital National Center for Disease Control and Public Health of Georgia National Institute of Diseases of the Chest and Hospital National Institute of Pneumology M. Nasta ASA ‐ Advanced Solutions Accelerator National University of Singapore Neumología y Alergología Infantil, Hospital La Fe Nippon Medical School Nova Southeastern University Trinidad and Clínica El Avila Observational and Pragmatic Research Institute Singapore Odense University Hospital Olmsted Medical Center Ospedale Policlino San Martino ‐University of Genoa Padua General University Hospital Peercode BV Association of Finnish Pharmacies Philipps-Universität Marburg Policlínica Geral do Rio de Janeiro Pulmonolory Research Institute FMBA Ukrainian Medical Stomatological Academy Rangueil-Larrey Hospital Rashid Hospital Regional hospital of ISSSTE Regione Liguria Regione Piemonte Regionie Puglia Rheinische Friedrich-Wilhelms-University Bonn Autonomous University of Madrid Russian National Research Medical University named Pirogov Saint Louis University School of Medicine Umeå University Salud Sector sanitario de Barbastro Salud Sector sanitario de Barbastro Sarno “Martiri del Villa Malta” Hospital Serviço de Imunoalergologia Hospital da Luz Showa University School of Medicine Sifmed Social Workers Coordinator Sociedad Paraguaya de Alergia Asma e Inmunología Autonomous Province of Trento Sorbonne Universités Univ Hospitals Leuven National and Kapodistrian University of Athens Universidad Autónoma de Nuevo León Hospital Vall d’Hebron Biomax Informatics AG Universidad Católica de Córdoba University of Sao Paulo Universidade do Estado do Pará Universidade do Porto Universidade Federal da Bahia Universidade Federal do Rio de Janeiro Universidade Federal dos Pampas Universita Cattolica del Sacro Cuore università di Salerno Hospital Zambrano Hellion Tec de Monterrey Universitaria San Martino Bon Secours Hospital Universitat Pompeu Fabra Universitätsklinikum Düsseldorf Universitätsmedizin der Johannes Gutenberg‐Universität Mainz Université Catholique de Louvain Université Claude Bernard Lyon Université Grenoble Alpes Université Joseph Fourier Université Paris-Saclay Humboldt-Universitat zu Berlin Université Paris-Sud Université Versailles Saint-Quentin Bradford Royal Infirmary Université Versailles Saint-Quentin University CEU San Pablo University Clinic of Respiratory and Allergic Diseases University College Cork University College London University Hospital ‘Sv. Ivan Rilski’ University Hospital Naples Royal Brompton Hospital University Hospital of Kinshasa University Hospital of Strasbourg University Hospital of Zurich Capital Institute of Pediatrics University Hospital Olomouc University J.J. Strossmayer University Montpellier University of Aberdeen University of Amsterdam University of Barcelona Imperial College London University of Bari Medical School University of Beira Interior University of Belgrade University of Bratislava Catholic University of Sacred Heart University of Cape Town University of Chile University of Coimbra University of Cologne University of Copenhagen Inserm U 1168 University of Crete University of Crete School of Medicine University of Cyprus University of Dundee The University of Edinburgh Manisa Celal Bayar University University of Ferrara University of Genoa University of Guadalajara University of Helsinki Institut du Thorax University of Leicester |
Publication Type: | Peer Reviewed |
| Appears in Collections: | Άρθρα/Articles |
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