Παρακαλώ χρησιμοποιήστε αυτό το αναγνωριστικό για να παραπέμψετε ή να δημιουργήσετε σύνδεσμο προς αυτό το τεκμήριο:
https://hdl.handle.net/20.500.14279/13862
Τίτλος: | MR monitoring of focused ultrasonic surgery of renal cortex: Experimental and simulation studies | Συγγραφείς: | Unger, Evan Colucci, Vincent Hynynen, Kullervo Damianou, Christakis A. Cline, Harvey H. Jolesz, Ferenc A. |
Major Field of Science: | Engineering and Technology | Field Category: | Electrical Engineering - Electronic Engineering - Information Engineering | Λέξεις-κλειδιά: | Hyperthermla;Kidney;MR;Kidney, surgery;Magnetic resonance (MR) guidance;Temperature monitoring;Ultrasound;Therapeutic | Ημερομηνία Έκδοσης: | 1-Μαΐ-1995 | Πηγή: | Journal of Magnetic Resonance Imaging, 1995, vol. 5, no. 3, pp. 259-266 | Volume: | 5 | Issue: | 3 | Start page: | 259 | End page: | 266 | Περιοδικό: | Journal of Magnetic Resonance Imaging | Περίληψη: | The aim of the study was to test the hypothesis that magnetic resonance (MR) imaging‐guided and ‐monitored noninvasive ultrasonic surgery can be performed in highly perfused tissues from outside the body. A simulation study was performed to evaluate the optimal sonication parameters. An MR‐compatible positioning device was then used to manipulate a focused ultrasound transducer in an MR imager, which was used to sonicate kidneys of five rabbits at various power levels and different durations. Temperature elevation during sonication was monitored with a T1‐ weighted spoiled gradient‐echo sequence. The simulation study demonstrated that a sharply focused transducer and relatively short sonication times (30 seconds or less) are necessary to prevent damage to the overlying skin and muscle tissue, which have a much lower blood perfusion rate than kidney. The experiments showed that the imaging sequence was sensitive enough to show temperature elevation during sonication, thereby Indicating the location of the beam focus. Histologic evaluations showed that kidney necrosis could be consistently induced without damage to overlying skin and muscle. The study demonstrated that highly perfused tissues such as the renal cortex can be coagulated from outside the body with focused ultrasound and that MR imaging can be used to guide and monitor this surgery. Copyright © 1995 Wiley‐Liss, Inc., A Wiley Company | ISSN: | 15222586 | DOI: | 10.1002/jmri.1880050306 | Rights: | © Wiley | Type: | Article | Affiliation: | Harvard University University of Arizona Health Sciences Center General Electric Company |
Publication Type: | Peer Reviewed |
Εμφανίζεται στις συλλογές: | Άρθρα/Articles |
CORE Recommender
SCOPUSTM
Citations
30
checked on 1 Φεβ 2024
WEB OF SCIENCETM
Citations
56
Last Week
0
0
Last month
0
0
checked on 29 Οκτ 2023
Page view(s)
271
Last Week
0
0
Last month
10
10
checked on 30 Αυγ 2024
Google ScholarTM
Check
Altmetric
Όλα τα τεκμήρια του δικτυακού τόπου προστατεύονται από πνευματικά δικαιώματα