Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14279/9889
Title: | Surveillance of device-associated infection rates and mortality in 3 greek intensive care units |
Authors: | Apostolopoulou, Eleni A. Raftopoulos, Vasilios Filntisis, Georgios A. Kithreotis, Prokopis Stefanidis, Evagelos Galanis, Petros Veldekis, Dimitrios |
metadata.dc.contributor.other: | Ραφτόπουλος, Βασίλειος |
Major Field of Science: | Medical and Health Sciences |
Field Category: | Health Sciences |
Keywords: | Intensive care units;Patients;Microbial |
Issue Date: | May-2013 |
Source: | American Journal of Critical Care, 2013, vol. 22, no. 3, pp. e12-e20 |
Volume: | 22 |
Issue: | 3 |
Start page: | 12 |
End page: | 20 |
Journal: | American Journal of Critical Care |
Abstract: | Background: Several studies suggest that device-associated, health care-associated infections (DA-HAIs) affect the quality of care in intensive care units, increasing patients' morbidity and mortality and the costs of patient care. Objectives: To assess the DA-HAIs rates, microbiological profile, antimicrobial resistance, and crude excess mortality in 3 intensive care units in Athens, Greece. Methods: A prospective cohort, active DA-HAI surveillance study was conducted in 3 Greek intensive care units from July 2009 to June 2010. The rates of mechanical ventilator-associated pneumonia (VAP), central catheter-associated bloodstream infection (CLABSI), and catheter-associated urinary tract infection (CAUTI) were calculated along with microbiological profile, antimicrobial resistance, and crude excess mortality. Results: During 6004 days in intensive care, 152 of 294 patients acquired 205 DA-HAIs, an overall rate of 51.7% of patients or 34.1 DA-HAIs per 1000 days (95% CI, 29.3-38.6). The VAP rate was 20 (95% CI, 16.3-23.7) per 1000 ventilator-days, the CLABSI rate was 11.8 (95% CI: 9.2-14.8) per 1000 catheter-days, and the CAUTI rate was 4.2 (95% CI, 2.5-5.9) per 1000 catheter-days. The most frequently isolated pathogen was Acinetobacter baumannii among patients with CLABSI (37.8%) and Candida species among patients with CAUTI (66.7%). Excess mortality was 20.3% for VAP and CLABSI and 32.2% for carbapenem-resistant A baumannii CLABSI. Conclusion: High rates of DA-HAIs, device utilization, and anti -microbial resistance emphasize the need for antimicrobial stewardship, the establishment of an active surveillance program of DA-HAIs, and the implementation of evidence-based preventive strategies. (American Journal of Critical Care. 2013;22:e12-e20). |
URI: | https://hdl.handle.net/20.500.14279/9889 |
ISSN: | 10623264 |
DOI: | 10.4037/ajcc2013324 |
Rights: | © NCBI |
Type: | Article |
Affiliation : | General and Oncological Hospital of Kiffissia Cyprus University of Technology National and Kapodistrian University of Athens Sotiria Hospital General Hospital of Attiki KAT |
Publication Type: | Peer Reviewed |
Appears in Collections: | Άρθρα/Articles |
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