Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/9889
Title: Surveillance of device-associated infection rates and mortality in 3 greek intensive care units
Authors: Apostolopoulou, Eleni A. 
Raftopoulos, Vasilios 
Filntisis, Georgios A. 
Kithreotis, Prokopis 
Stefanidis, Evagelos 
Galanis, Petros 
Veldekis, Dimitrios 
metadata.dc.contributor.other: Ραφτόπουλος, Βασίλειος
Major Field of Science: Medical and Health Sciences
Field Category: Health Sciences
Keywords: Intensive care units;Patients;Microbial
Issue Date: May-2013
Source: American Journal of Critical Care, 2013, vol. 22, no. 3, pp. e12-e20
Volume: 22
Issue: 3
Start page: 12
End page: 20
Journal: American Journal of Critical Care 
Abstract: Background: Several studies suggest that device-associated, health care-associated infections (DA-HAIs) affect the quality of care in intensive care units, increasing patients' morbidity and mortality and the costs of patient care. Objectives: To assess the DA-HAIs rates, microbiological profile, antimicrobial resistance, and crude excess mortality in 3 intensive care units in Athens, Greece. Methods: A prospective cohort, active DA-HAI surveillance study was conducted in 3 Greek intensive care units from July 2009 to June 2010. The rates of mechanical ventilator-associated pneumonia (VAP), central catheter-associated bloodstream infection (CLABSI), and catheter-associated urinary tract infection (CAUTI) were calculated along with microbiological profile, antimicrobial resistance, and crude excess mortality. Results: During 6004 days in intensive care, 152 of 294 patients acquired 205 DA-HAIs, an overall rate of 51.7% of patients or 34.1 DA-HAIs per 1000 days (95% CI, 29.3-38.6). The VAP rate was 20 (95% CI, 16.3-23.7) per 1000 ventilator-days, the CLABSI rate was 11.8 (95% CI: 9.2-14.8) per 1000 catheter-days, and the CAUTI rate was 4.2 (95% CI, 2.5-5.9) per 1000 catheter-days. The most frequently isolated pathogen was Acinetobacter baumannii among patients with CLABSI (37.8%) and Candida species among patients with CAUTI (66.7%). Excess mortality was 20.3% for VAP and CLABSI and 32.2% for carbapenem-resistant A baumannii CLABSI. Conclusion: High rates of DA-HAIs, device utilization, and anti -microbial resistance emphasize the need for antimicrobial stewardship, the establishment of an active surveillance program of DA-HAIs, and the implementation of evidence-based preventive strategies. (American Journal of Critical Care. 2013;22:e12-e20).
URI: https://hdl.handle.net/20.500.14279/9889
ISSN: 10623264
DOI: 10.4037/ajcc2013324
Rights: © NCBI
Type: Article
Affiliation : General and Oncological Hospital of Kiffissia 
Cyprus University of Technology 
National and Kapodistrian University of Athens 
Sotiria Hospital 
General Hospital of Attiki KAT 
Publication Type: Peer Reviewed
Appears in Collections:Άρθρα/Articles

CORE Recommender
Sorry the service is unavailable at the moment. Please try again later.
Show full item record

SCOPUSTM   
Citations

19
checked on Nov 9, 2023

WEB OF SCIENCETM
Citations

16
Last Week
0
Last month
0
checked on Nov 1, 2023

Page view(s)

502
Last Week
2
Last month
20
checked on Apr 2, 2025

Google ScholarTM

Check

Altmetric


Items in KTISIS are protected by copyright, with all rights reserved, unless otherwise indicated.