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Title: Incidence of Sudden Cardiac Death in a Young Active Population
Authors: Farioli, Andrea 
Christophi, Costas A. 
Quarta, Candida Cristina 
Kales, Stefanos N. 
Major Field of Science: Medical and Health Sciences
Field Category: Clinical Medicine
Keywords: Death;Epidemiology;Men;Registries;Statistics;Sudden
Issue Date: 11-Jun-2015
Source: Journal of the American Heart Association, 2015, vol. 4, no. 6.
Volume: 4
Issue: 6
DOI: 10.1161/JAHA.115.001818
Journal: Journal of the American Heart Association 
Abstract: Background--Little is known about the burden of sudden cardiac death (SCD) among active, presumably healthy persons. Weinvestigated the incidence of SCD among US male career firefighters.Methods and Results--All on-duty SCDs among US male career firefighters between 1998 and 2012 were identified from theUS Fire Administration and the US National Institute for Occupational Safety and Health databases. Age-specific incidence rates(IRs) of SCD with 95% CIs were computed. A joinpoint model was fitted to analyze the trend in IR and to help estimate the annualpercentage change of SCD rates over the years. The effects of seasonality were assessed through a Poisson regression model.We identified 182 SCDs; based on 99 available autopsy reports, the leading underlying cause of death was coronary heartdisease (79%). The overall IR was 18.1 SCDs per 100 000 person-years. The age-specific IRs of SCD ranged between 3.8 (forthose aged 18 to 24 years) and 45.2 (for those aged 55 to 64 years) per 100 000 person-years. The annual rate of SCD steadilydeclined over time (annual percentage change 3.9%, 95% CI 5.8 to 2.0). SCD events were more frequent during January(peak-to-low ratio 1.70; 95% CI 1.09 to 2.65). In addition, the IR was 3 times higher during high-risk duties compared with lowriskduties. IRs among firefighters were lower than those observed among the US general population and US military personnel.Conclusions--SCD risk in this active working population is overestimated using statistics from the general population. To addresspublic health questions among these subpopulations, more specific studies of active adults should be conducted.
ISSN: 2047-9980
DOI: 10.1161/JAHA.115.001818
Rights: © 2015 The Authors.
Type: Article
Affiliation : Harvard University 
University of Bologna 
Cyprus University of Technology 
S.Orsola-Malpighi Polyclinic 
Appears in Collections:Άρθρα/Articles

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