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Πεδίο DCΤιμήΓλώσσα
dc.contributor.authorExarchou, Vassiliki-
dc.contributor.authorKanetis, Loukas-
dc.contributor.authorCharalambous, Zenovia-
dc.contributor.authorApers, Sandra-
dc.contributor.authorPieters, Luc A C-
dc.contributor.authorGekas, Vassilis-
dc.contributor.authorGoulas, Vlasios-
dc.date.accessioned2017-02-01T14:24:36Z-
dc.date.available2017-02-01T14:24:36Z-
dc.date.issued2015-01-12-
dc.identifier.citationJournal of Agricultural and Food Chemistry, 2015, vol. 63, no. 2, pp. 457-463.en_US
dc.identifier.issn00218561-
dc.identifier.urihttps://hdl.handle.net/20.500.14279/9364-
dc.description.abstractPlant pathogenic fungi are considered of significant economic importance for adversely affecting both quantitatively and qualitatively fresh and processed produce. Extracts of Salvia fruticosa were initially screened for their antifungal activity, and the ethyl acetate fraction, being the most active, was further analyzed using HPLC-SPE-NMR hyphenation. The methoxylated flavones hispidulin, salvigenin, and cirsimaritin and the diterpenes carnosic acid, carnosol, and 12-methoxycarnosic acid were identified as the major components of the extract. In addition, the concentration levels of all identified components were determined using q-NMR. The antifungal activity of the crude extract and selected phytochemicals was estimated against the fungal species Aspergillus tubingensis, Botrytis cinerea, and Penicillium digitatum. The estimated MIC and MFC values of the ethyl acetate extract of S. fruticosa, as well as three of its major constituents, carnosic acid, carnosol, and hispidulin, support their antifungal activity, especially against B. cinerea and P. digitatum, suggesting their potential use in food and agricultural systems.en_US
dc.formatpdfen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Agricultural and Food Chemistryen_US
dc.rights© American Chemical Society.en_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectAspergillus tubingensisen_US
dc.subjectBotrytis cinereaen_US
dc.subjectGreek sageen_US
dc.subjectPenicillium digitatumen_US
dc.subjectditerpenesen_US
dc.subjectflavonoidsen_US
dc.subjectphytochemicalsen_US
dc.subjectq-NMRen_US
dc.titleHPLC-SPE-NMR characterization of major metabolites in Salvia fruticosa mill. Extract with antifungal potential: Relevance of carnosic acid, carnosol, and hispidulinen_US
dc.typeArticleen_US
dc.doi10.1021/jf5050734en_US
dc.collaborationCyprus University of Technologyen_US
dc.subject.categoryAgricultural Biotechnologyen_US
dc.journalsOpen Accessen_US
dc.countryCyprusen_US
dc.countryBelgiumen_US
dc.subject.fieldAgricultural Sciencesen_US
dc.publicationPeer Revieweden_US
dc.identifier.doi10.1021/jf5050734en_US
dc.relation.issue2en_US
dc.relation.volume63en_US
cut.common.academicyear2014-2015en_US
dc.identifier.spage457en_US
dc.identifier.epage469en_US
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.cerifentitytypePublications-
item.openairetypearticle-
crisitem.journal.journalissn1520-5118-
crisitem.journal.publisherAmerican Chemical Society-
crisitem.author.deptDepartment of Agricultural Sciences, Biotechnology and Food Science-
crisitem.author.deptDepartment of Agricultural Sciences, Biotechnology and Food Science-
crisitem.author.deptDepartment of Agricultural Sciences, Biotechnology and Food Science-
crisitem.author.facultyFaculty of Geotechnical Sciences and Environmental Management-
crisitem.author.facultyFaculty of Geotechnical Sciences and Environmental Management-
crisitem.author.facultyFaculty of Geotechnical Sciences and Environmental Management-
crisitem.author.orcid0000-0002-1869-558X-
crisitem.author.orcid0000-0003-3502-2210-
crisitem.author.orcid0000-0001-7527-1559-
crisitem.author.parentorgFaculty of Geotechnical Sciences and Environmental Management-
crisitem.author.parentorgFaculty of Geotechnical Sciences and Environmental Management-
crisitem.author.parentorgFaculty of Geotechnical Sciences and Environmental Management-
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