1. Ktisis Cyprus University of Technology
  2. Cyprus University of Technology (Research Output)
  3. Δημοσιεύσεις σε συνέδρια /Conference papers or poster or presentation
Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/9113
DC FieldValueLanguage
dc.contributor.authorYiannakou, Marinos-
dc.contributor.authorDamianou, Christakis A.-
dc.contributor.otherΓιαννακού, Μαρίνος-
dc.contributor.otherΔαμιανού, Χριστάκης Α.-
dc.date.accessioned2017-01-18T14:43:58Z-
dc.date.available2017-01-18T14:43:58Z-
dc.date.issued2015-12-28-
dc.identifier.citation15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015; Belgrade; Serbia; 2 November 2015 through 4 November 2015en_US
dc.identifier.isbn978-146737983-0-
dc.identifier.urihttps://hdl.handle.net/20.500.14279/9113-
dc.description.abstractThe main objective of the study was to treat Alzheimer's disease (AD) plaques using focused ultrasound (FUS) induced blood brain barrier (BBB) opening with and without delivery of antibodies in a rabbit model for AD. The animal model was achieved by feeding a high cholesterol diet to rabbits for 4 months. A single spherically focused MRI compatible transducer was used which operated at 1 MHz, had a focal length of 10 cm and diameter of 4 cm. By increasing the number of sessions, the number of plaques decreased (both for antibodies, and without antibodies). This study demonstrated that by opening the BBB, it will be possible to deliver exogenous antibodies to the brain, which eliminates Amyloid β plaques.en_US
dc.formatpdfen_US
dc.language.isoenen_US
dc.rights© 2015 IEEE.en_US
dc.subjectAlzheimeren_US
dc.subjectAmyloid betaplaqueen_US
dc.subjectΑntibodyen_US
dc.subjectΒrainen_US
dc.subjectFocused ultrasounden_US
dc.subjectMRIen_US
dc.titleAmyloid beta plaque reduction with antibodies crossing the blood brain barrier opened with focused ultrasound in a rabbit modelen_US
dc.typeConference Papersen_US
dc.doi10.1109/BIBE.2015.7367707en_US
dc.collaborationCyprus University of Technologyen_US
dc.subject.categoryClinical Medicineen_US
dc.countryCyprusen_US
dc.subject.fieldMedical and Health Sciencesen_US
dc.publicationPeer Revieweden_US
dc.relation.conferenceIEEE International Conference on Bioinformatics and Bioengineeringen_US
cut.common.academicyear2014-2015en_US
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_c94f-
item.openairetypeconferenceObject-
item.grantfulltextnone-
item.languageiso639-1en-
item.cerifentitytypePublications-
crisitem.author.deptDepartment of Mechanical Engineering and Materials Science and Engineering-
crisitem.author.deptDepartment of Electrical Engineering, Computer Engineering and Informatics-
crisitem.author.facultyFaculty of Engineering and Technology-
crisitem.author.facultyFaculty of Engineering and Technology-
crisitem.author.orcid0000-0003-0424-2851-
crisitem.author.parentorgFaculty of Engineering and Technology-
crisitem.author.parentorgFaculty of Engineering and Technology-
Appears in Collections:Δημοσιεύσεις σε συνέδρια /Conference papers or poster or presentation
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