Could Pragmatic Clinical Trials be Effective in the Management of Patients with Heart Failure?
Journal
American Journal of Biomedical Science and Research
Date Issued
April 30, 2024
Author(s)
Abstract
Pragmatic Clinical Trials (PCT) seem to be popular nowadays
and can be used to test the effectiveness of health interventions
avoiding the restrictions associated with traditional explanatory randomized clinical trials. The pragmatic methodology design
is promising for chronic diseases like Heart Failure (HF) and comorbidities. HF has been mentioned as the most malignant type
of Cardiovascular-Disease (CVD) and has the same aggravation of
symptoms and survival rates, as the most types of cancer [1,2]. It
is a syndrome characterized by symptoms that persist; breathlessness, fatigue and swelling of ankles. All these symptoms affect the
Health-Related Quality of Life (HR-QoL) and the ability of the patients to maintain self-care management [3-5]. HF in diabetic patients is an important health problem and DM is a major risk factor
in HF and vice versa [6,7]. HF and DM most of the time occur together, aggravating each condition and exacerbates patient outcomes
[8,9].
and can be used to test the effectiveness of health interventions
avoiding the restrictions associated with traditional explanatory randomized clinical trials. The pragmatic methodology design
is promising for chronic diseases like Heart Failure (HF) and comorbidities. HF has been mentioned as the most malignant type
of Cardiovascular-Disease (CVD) and has the same aggravation of
symptoms and survival rates, as the most types of cancer [1,2]. It
is a syndrome characterized by symptoms that persist; breathlessness, fatigue and swelling of ankles. All these symptoms affect the
Health-Related Quality of Life (HR-QoL) and the ability of the patients to maintain self-care management [3-5]. HF in diabetic patients is an important health problem and DM is a major risk factor
in HF and vice versa [6,7]. HF and DM most of the time occur together, aggravating each condition and exacerbates patient outcomes
[8,9].
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