Chrono-modulated effects of external stressors on oxidative stress and damage in humans: A scoping review on night shift work
Journal
Environment International
Date Issued
August 2023
DOI
10.1016/j.envint.2023.108048
Abstract
Oxidative stress and tissue damage (OSD) play a pivotal role as an early-stage process in chronic disease pathogenesis. However, there has been little research to better understand the temporal (χρόνος[chronos]) dimensions of OSD process associated with environmental (non-genetic, including behaviors/lifestyle) and/or occupational stressors, like night shift work. OSD processes have recently attracted attention in relation to time-resolved external stressor trajectories in personalized medicine (prevention) initiatives, as they seem to interact with circadian clock systems towards the improved delineation of the early stages of (chronic) disease process.
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