Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14279/26582
Title: | Pediatric asthma symptom control during lockdown for the COVID-19 pandemic in Spring 2020: A prospective community-based study in Cyprus and Greece | Authors: | Kouis, Panayiotis Michaelidou, Eleni Kinni, Paraskevi Michanikou, Antonis Anagnostopoulou, Pinelopi Dimitriou, Helen Karanicolas, Kostas Matthaiou, Andreas M. Achilleos, Souzana Papatheodorou, Stefania Koutrakis, Petros Middleton, Nicos Galanakis, Emmanouil Yiallouros, Panayiotis K. |
Major Field of Science: | Medical and Health Sciences | Field Category: | Health Sciences | Keywords: | Asthma;c‐ACT;COVID‐19;Lockdown;SARS‐CoV‐2;Schoolchildren | Issue Date: | Feb-2022 | Source: | Pediatric Pulmonology, 2022, vol. 57, no. 2, pp. 386–394 | Volume: | 57 | Issue: | 2 | Start page: | 386 | End page: | 394 | Journal: | Pediatric Pulmonology | Abstract: | Objectives To prospectively quantify at the community level changes in asthma symptom control and other morbidity indices, among asthmatic schoolchildren in response to coronavirus disease 2019 (COVID-19) lockdown measures. Methods In Spring 2019 and Spring 2020, we prospectively assessed monthly changes in pediatric asthma control test (c-ACT), asthma medication usage, infections and unscheduled visits for asthma among schoolchildren with active asthma in Cyprus and Greece. We compared asthma symptom control and other morbidity indices before and during lockdown measures, while participants’ time spent at home was objectively assessed by wearable sensors. Results A total of 119 asthmatic children participated in the study during Spring 2020. Compared to a mean baseline (pre-COVID-19 lockdown) c-ACT score of 22.70, adjusted mean increases of 2.58 (95% confidence interval [CI]: 1.91, 3.26, p < 0.001) and 3.57 (95% CI: 2.88, 4.27, p < 0.001) in the 2nd and 3rd monthly assessments were observed after implementation of lockdown measures. A mean increase in c-ACT score of 0.32 (95% CI: 0.17, 0.47, p < 0.001) was noted per 10% increase in the time spent at home. Improvement was more profound in children with severe asthma, while significant reductions in infections, asthma medication usage and unscheduled visits for asthma were also observed. During Spring 2019, 39 children participated in the study in the absence of lockdown measures and no changes in c-ACT or other indices of disease severity were observed. Conclusions Clinically meaningful improvements in asthma symptom control, among asthmatic schoolchildren were observed during the COVID-19 lockdown measures in Spring 2020. Improvements were independently associated with time spent at home and were more profound in the children with severe asthma. | URI: | https://hdl.handle.net/20.500.14279/26582 | ISSN: | 10990496 | DOI: | 10.1002/ppul.25765 | Rights: | © Wiley | Type: | Article | Affiliation : | University of Cyprus University of Crete University of Bern Cyprus University of Technology Harvard University |
Publication Type: | Peer Reviewed |
Appears in Collections: | Άρθρα/Articles |
CORE Recommender
SCOPUSTM
Citations
5
checked on Feb 1, 2024
WEB OF SCIENCETM
Citations
3
Last Week
0
0
Last month
0
0
checked on Oct 29, 2023
Page view(s)
289
Last Week
0
0
Last month
1
1
checked on Dec 22, 2024
Google ScholarTM
Check
Altmetric
This item is licensed under a Creative Commons License