Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/26550
Title: In-vitro biomechanical studies of endovascular devices
Authors: Kapnisis, Konstantinos 
Halwani, Dina O. 
Anderson, Peter G. 
Brott, Brigitta C. 
Lemons, Jack E. 
Anayiotos, Andreas 
Major Field of Science: Engineering and Technology
Field Category: Materials Engineering
Keywords: Stainless steel stents;Nickel titanium stents
Issue Date: 27-Apr-2010
Source: Nanotheranostics International Conference, 2010, 27-30 April, Ayia Napa, Cyprus
Conference: Nanotheranostics international conference 
Abstract: Preliminary studies have revealed that stainless steel (SS) and nickel titanium (NiTi) stents undergo corrosion in vivo, with significant release of metallic ions into surrounding tissues. It is believed that high concentrations of metal ions from both SS and NiTi stents are toxic to vascular smooth muscle cells and stimulate both inflammatory and fibrotic reactions leading to neointimal formation and a predisposition to device failure. To separate the mechanical effects from the local environmental effects on the stent surface, invitro mechanical studies were performed on various combinations of stents under low and high curvature and in overlapping positions to compare the results of fretting, pitting and gouging with the explanted stents.
URI: https://hdl.handle.net/20.500.14279/26550
Type: Conference Papers
Affiliation : Cyprus University of Technology 
University of Alabama at Birmingham 
Publication Type: Peer Reviewed
Appears in Collections:Δημοσιεύσεις σε συνέδρια /Conference papers or poster or presentation

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