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Πεδίο DCΤιμήΓλώσσα
dc.contributor.authorKranou-Economidou, Despina-
dc.contributor.authorKambanaros, Maria-
dc.date.accessioned2021-09-30T10:14:53Z-
dc.date.available2021-09-30T10:14:53Z-
dc.date.issued2022-
dc.identifier.citationAphasiology, 2022, vol. 36, no. 1, pp. 51-75en_US
dc.identifier.issn14645041-
dc.identifier.urihttps://hdl.handle.net/20.500.14279/23151-
dc.description.abstractBackground: Intermittent theta burst stimulation (iTBS) administered to the left dorsolateral prefrontal cortex (LDLPFC) has been shown to advance working memory (WM) abilities. At the same time, WM training is widely used to enhance learning associated with low language skills. An emerging area of research is that of applying cortical stimulation as an adjunct to behavioural therapy to improve language abilities in people with aphasia (PWA) after stroke. Aim: The aim of this study was to pilot the efficacy of the iTBS protocol, targeting the LDLPFC in combination with computerized WM training by measuring the near-transfer effects on WM and fluid intelligence (Gf) and far-transfer effects on language functioning and quality of life (QoL) in an individual with stroke-induced chronic aphasia. Methods & Procedures: The participant was a 31-year old female who presented with chronic non-fluent aphasia, following a left-hemisphere stroke involving the left frontoparietal lobes. She showed prominent anomia with frequent occurrences of word-finding difficulties. The assessment battery included a screening measure of WM, a standardized aphasia battery, a non-verbal intelligence test, spontaneous speech samples, a procedural discourse task, and a questionnaire addressing quality of life. All measures were administered once at baseline, immediately after treatment was terminated, and once during follow-up testing, at 3 months post-treatment. The treatment program included 10 consecutive daily sessions of 30-minutes computer-assisted WM training preceded by 3-minutes of iTBS. Outcomes & Results: Statistically significant improvement from baseline to post-treatment was found only for the non-verbal intelligence measure, suggesting near-transfer effects. There was no improvement on the computerized WM screening measure. Although no other measures revealed a statistically significant difference, there was a trend towards better performance on untreated items of receptive and expressive language tasks (far-transfer). Conclusions: The findings revealed a trend for improvement in receptive and expressive language abilities in one individual with chronic aphasia. The iTBS protocol in combination with computerised WM training could be a promising treatment but further studies with larger number of participants are needed to establish its effectiveness for improvement of aphasia after stroke.en_US
dc.formatpdfen_US
dc.language.isoenen_US
dc.relation.ispartofAphasiologyen_US
dc.rights© Taylor & Francisen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAphasiaen_US
dc.subjectCognitionen_US
dc.subjectReceptive and expressive languageen_US
dc.subjectTranscranial Magnetic Stimulation (TMS)en_US
dc.subjectWorking memoryen_US
dc.titleCombining Intermittent Theta Burst Stimulation (iTBS) With Computerized Working Memory Training to Improve Language Abilities in Chronic Aphasia: A Pilot Case Studyen_US
dc.typeArticleen_US
dc.collaborationCyprus University of Technologyen_US
dc.collaborationUniversity of South Australiaen_US
dc.subject.categoryClinical Medicineen_US
dc.journalsSubscriptionen_US
dc.countryCyprusen_US
dc.countryAustraliaen_US
dc.subject.fieldMedical and Health Sciencesen_US
dc.publicationPeer Revieweden_US
dc.identifier.doi10.1080/02687038.2020.1852165en_US
dc.identifier.scopus2-s2.0-85097901902-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85097901902-
dc.relation.issue1en_US
dc.relation.volume36en_US
cut.common.academicyear2021-2022en_US
dc.identifier.spage51en_US
dc.identifier.epage75en_US
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.cerifentitytypePublications-
item.openairetypearticle-
crisitem.journal.journalissn0268-7038-
crisitem.journal.publisherTaylor & Francis-
crisitem.author.deptDepartment of Rehabilitation Sciences-
crisitem.author.deptDepartment of Rehabilitation Sciences-
crisitem.author.facultyFaculty of Health Sciences-
crisitem.author.facultyFaculty of Health Sciences-
crisitem.author.orcid0000-0002-8431-3594-
crisitem.author.orcid0000-0002-5857-9460-
crisitem.author.parentorgFaculty of Health Sciences-
crisitem.author.parentorgFaculty of Health Sciences-
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