Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14279/22747
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Alekou, Tereza | - |
dc.contributor.author | Giannakou, Marinos | - |
dc.contributor.author | Damianou, Christakis A. | - |
dc.date.accessioned | 2021-06-22T06:56:56Z | - |
dc.date.available | 2021-06-22T06:56:56Z | - |
dc.date.issued | 2021-02 | - |
dc.identifier.citation | Ultrasonics, 2021, vol. 110, articl. no. 106244 | en_US |
dc.identifier.issn | 0041624X | - |
dc.identifier.uri | https://hdl.handle.net/20.500.14279/22747 | - |
dc.description.abstract | In this paper a high intensity focused ultrasound (FUS) phantom model was developed, in order to be used in experiments for Blood Brain Barrier (BBB) disruption. The target was to create a phantom model that represents the disruption of the BBB during ultrasound application. An appropriate experimental setup was created bearing a single element transducer with diameter 50 mm and geometric focus 100 mm operating at 0.5 MHz. It included a set of tubes and a connector with multiple 0.4 mm openings, through which a suitable liquid is being circulated with a pump. The lesions were sealed with a thin homogenous layer of wax, preventing a liquid leakage. The system was tested successfully with FUS and a liquid leakage was achieved after FUS application. This set up is the first phantom model that has the potential to be utilized as a cost-effective solution for performing experiments for BBB disruption, without the need of using animal models. | en_US |
dc.format | en_US | |
dc.language.iso | en | en_US |
dc.relation.ispartof | Ultrasonics | en_US |
dc.rights | © Elsevier | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | BBB | en_US |
dc.subject | FUS | en_US |
dc.subject | Phantom | en_US |
dc.subject | Ultrasound | en_US |
dc.title | Focused ultrasound phantom model for blood brain barrier disruption | en_US |
dc.type | Article | en_US |
dc.collaboration | Cyprus University of Technology | en_US |
dc.subject.category | Clinical Medicine | en_US |
dc.journals | Subscription | en_US |
dc.country | Cyprus | en_US |
dc.subject.field | Medical and Health Sciences | en_US |
dc.publication | Peer Reviewed | en_US |
dc.identifier.doi | 10.1016/j.ultras.2020.106244 | en_US |
dc.identifier.pmid | 32942090 | - |
dc.identifier.scopus | 2-s2.0-85090844895 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85090844895 | - |
dc.relation.volume | 110 | en_US |
cut.common.academicyear | 2020-2021 | en_US |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
item.openairetype | article | - |
crisitem.author.dept | Department of Electrical Engineering, Computer Engineering and Informatics | - |
crisitem.author.faculty | Faculty of Engineering and Technology | - |
crisitem.author.orcid | 0000-0003-0424-2851 | - |
crisitem.author.parentorg | Faculty of Engineering and Technology | - |
crisitem.journal.journalissn | 0041-624X | - |
crisitem.journal.publisher | Elsevier | - |
Appears in Collections: | Άρθρα/Articles |
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