Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/22712
DC FieldValueLanguage
dc.contributor.authorGrant, Rebecca-
dc.contributor.authorDub, Timothée-
dc.contributor.authorAndrianou, Xanthi-
dc.contributor.authorNohynek, Hanna-
dc.contributor.authorWilder-Smith, Annelies-
dc.contributor.authorPezzotti, Patrizio-
dc.contributor.authorFontanet, Arnaud-
dc.date.accessioned2021-06-17T06:59:34Z-
dc.date.available2021-06-17T06:59:34Z-
dc.date.issued2021-04-01-
dc.identifier.citationBMJ Open, 2021, vol. 11, no. 4, articl. no. e045425en_US
dc.identifier.issn2044-6055-
dc.identifier.urihttps://hdl.handle.net/20.500.14279/22712-
dc.description.abstractObjectives We aimed to review SARS-CoV-2 seroprevalence studies conducted in Europe to understand how they may be used to inform ongoing control strategies for COVID-19. Design Scoping review of peer-reviewed publications and manuscripts on preprint servers from January 2020 to 15 September 2020. Primary measure Seroprevalence estimate (and lower and upper CIs). For studies conducted across a country or territory, we used the seroprevalence estimate and the upper and lower CIs and compared them to the total number of reported infections to calculate the ratio of reported to expected infections. Results We identified 23 population-based seroprevalence studies conducted in Europe. Among 12 general population studies, seroprevalence ranged from 0.42% among residual clinical samples in Greece to 13.6% in an area of high transmission in Gangelt, Germany. Of the eight studies in blood donors, seroprevalence ranged from 0.91% in North-Western Germany to 23.3% in a high-transmission area in Lombardy region, Italy. In three studies which recruited individuals through employment, seroprevalence ranged from 0.5% among factory workers in Frankfurt, Germany, to 10.2% among university employees in Milan, Italy. In comparison to nationally reported cases, the extent of infection, as derived from these seroprevalence estimates, is manyfold higher and largely heterogeneous. Conclusion Exposure to the virus in Europe has not reached a level of infection that would prevent further circulation of the virus. Effective vaccine candidates are urgently required to deliver the level of immunity in the population.en_US
dc.formatpdfen_US
dc.language.isoenen_US
dc.relation.ispartofBMJ openen_US
dc.rights© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use.en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectEpidemiologyen_US
dc.subjectPublic healthen_US
dc.titleSARS-CoV-2 population-based seroprevalence studies in Europe: a scoping reviewen_US
dc.typeArticleen_US
dc.collaborationInstitut Pasteuren_US
dc.collaborationFinnish Institute for Health and Welfareen_US
dc.collaborationItalian National Health Instituteen_US
dc.collaborationCyprus University of Technologyen_US
dc.collaborationLondon School of Hygiene and Tropical Medicineen_US
dc.collaborationUniversity of Heidelbergen_US
dc.collaborationConservatoire National des Arts et Métiersen_US
dc.subject.categoryHealth Sciencesen_US
dc.journalsOpen Accessen_US
dc.countryFranceen_US
dc.countryFinlanden_US
dc.countryItalyen_US
dc.countryCyprusen_US
dc.countryUnited Kingdomen_US
dc.countryGermanyen_US
dc.subject.fieldMedical and Health Sciencesen_US
dc.publicationPeer Revieweden_US
dc.identifier.doi10.1136/bmjopen-2020-045425en_US
dc.identifier.pmid33795310-
dc.identifier.scopus2-s2.0-85103772543-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85103772543-
dc.relation.issue4en_US
dc.relation.volume11en_US
cut.common.academicyear2020-2021en_US
item.cerifentitytypePublications-
item.languageiso639-1en-
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.openairetypearticle-
item.grantfulltextopen-
crisitem.journal.journalissn2044-6055-
crisitem.journal.publisherBMJ-
crisitem.author.deptCyprus International Institute for Environmental and Public Health-
crisitem.author.facultyFaculty of Health Sciences-
crisitem.author.orcid0000-0002-2906-5743-
crisitem.author.parentorgFaculty of Health Sciences-
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