Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14279/18536
Title: | Structural Basis for Allosteric Regulation in the Major Antenna Trimer of Photosystem II | Authors: | Daskalakis, Vangelis Maity, Sayan Hart, Cameron Lewis Stergiannakos, Taxiarchis Duffy, Christopher D P Kleinekathöfer, Ulrich |
Major Field of Science: | Natural Sciences | Field Category: | Biological Sciences | Keywords: | Allosteric regulation;Environmental conditions;Molecular simulations | Issue Date: | 14-Nov-2019 | Source: | The Journal of Physical Chemistry B, 2019, vol. 123, no. 45, pp. 9609-9615 | Volume: | 123 | Issue: | 45 | Start page: | 9609 | End page: | 9615 | Journal: | The Journal of Physical Chemistry B | Abstract: | The allosteric regulation of protein function proves important in many life-sustaining processes. In plant photosynthesis, LHCII, the major antenna complex of Photosystem II, employs a delicate switch between light harvesting and photoprotective modes. The switch is triggered by an enlarged pH gradient (ΔpH) across the thylakoid membranes. Using molecular simulations and quantum calculations, we show that ΔpH can tune the light-harvesting potential of the antenna via allosteric regulation of the excitonic coupling in chlorophyll-carotenoid pairs. To this end, we propose how the LHCII excited state lifetime is coupled to the environmental conditions. In line with experimental findings, our theoretical model provides crucial evidence toward the elucidation of the photoprotective switch of higher plants at an all-atom resolution. | URI: | https://hdl.handle.net/20.500.14279/18536 | ISSN: | 15205207 | DOI: | 10.1021/acs.jpcb.9b09767 | Rights: | © American Chemical Society Attribution-NonCommercial-NoDerivs 3.0 United States |
Type: | Article | Affiliation : | Cyprus University of Technology Jacobs University Bremen Queen Mary University of London |
Publication Type: | Peer Reviewed |
Appears in Collections: | Άρθρα/Articles |
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