Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/18493
Title: Effect of different macromolecules on viscous and microrheologic properties of blood at various temperatures
Authors: Ermolinskiy, Petr B. 
Semenov, Alexei N. 
Lugovtsov, Andrei E. 
Poeschl, Christina 
Windberger, Ursula 
Kaliviotis, Efstathios 
Priezzhev, Alexander V. 
Major Field of Science: Engineering and Technology
Field Category: Mechanical Engineering
Keywords: Aggregation;Dextran 150;Dextran 500;Erythrocytes;RBCs;Temperature;Viscosity
Issue Date: 3-Jun-2019
Source: International Symposium on Optics and Biophotonics VI: Saratov Fall Meeting, 2018, 24-28 September, Saratov, Russian Federation
Conference: International Symposium on Optics and Biophotonics 
Abstract: Microrheological parameters of red blood cells (RBCs) and blood viscosity were studied by different optical and rheometric techniques. Measurements were performed under in vitro condition both on the EDTA-stabilized whole blood samples at various temperatures and on the RBCs in autologous serum without platelets at different concentrations of proaggregant macromolecules (Dextran 150, Dextran 500 and albumin). The nonlinear dependences of the aggregation parameters on the concentration of the proaggregant macromolecules in autologous serum were observed. Rheometry of human whole blood samples demonstrates a power law dependence of the suspension viscosity on temperature at such shear rates that allow the RBC aggregation. We assume that there may be an unaccounted temperature dependent synergetic effect of plasma proteins/macromolecules on RBC aggregation and interaction and, consequently, on the blood viscosity.
Description: This work was supported by RFBR grant № 17-02-01200-a.
URI: https://hdl.handle.net/20.500.14279/18493
DOI: 10.1117/12.2523688
Rights: © SPIE
Type: Conference Papers
Affiliation : Lomonosov Moscow State University 
Medical University of Vienna 
Cyprus University of Technology 
Publication Type: Peer Reviewed
Appears in Collections:Δημοσιεύσεις σε συνέδρια /Conference papers or poster or presentation

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