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https://hdl.handle.net/20.500.14279/13451
Πεδίο DC | Τιμή | Γλώσσα |
---|---|---|
dc.contributor.author | Smith, Denise Louise | - |
dc.contributor.author | Haller, Jeannie M. | - |
dc.contributor.author | Korre, Maria | - |
dc.contributor.author | Fehling, Patricia C. | - |
dc.contributor.author | Sampani, Konstantina | - |
dc.contributor.author | Grossi Porto, Luiz Guilherme | - |
dc.contributor.author | Christophi, Costas A. | - |
dc.contributor.author | Kales, Stefanos N. | - |
dc.date.accessioned | 2019-04-05T09:19:06Z | - |
dc.date.available | 2019-04-05T09:19:06Z | - |
dc.date.issued | 2018-09-01 | - |
dc.identifier.citation | Journal of the American Heart Association, 2018, vol. 7, no. 18 | en_US |
dc.identifier.issn | 20479980 | - |
dc.description.abstract | Background Sudden cardiac death accounts for the greatest proportion of duty-related deaths among US firefighters. Increased understanding of the pathoanatomic causes of sudden cardiac death and the risk associated with underlying cardiac pathologies is needed to develop evidence-based screening recommendations. Methods and Results Using autopsy data for duty-related firefighter fatalities occurring between 1999 and 2014, this retrospective case-control study compared cardiac findings of male firefighters aged 18 to 65 years who died on duty of cardiac-related causes with those who died of noncardiac trauma-related causes. Data from 276 cardiac cases and 351 noncardiac trauma controls were analyzed. Among cardiac cases, the most prevalent (82%) underlying pathoanatomic substrate was comorbid coronary heart disease and cardiomegaly/left ventricular hypertrophy. Cardiac cases had a higher prevalence of cardiomegaly (heart weight >450 g), left ventricular hypertrophy (left ventricular wall thickness ≥1.2 cm), and severe coronary artery stenosis (≥75%) than trauma controls (all P<0.001). In multivariate analyses, heart weight >450 g, coronary artery stenosis ≥75%, and evidence of a prior myocardial infarction were strong independent predictors of cardiac death, with odds ratios of 6.1 (95% confidence interval, 3.6-10.4), 9.3 (95% confidence interval, 5.3-16.1), and 6.2 (95% confidence interval, 3.4-11.3), respectively. Conclusions The majority of cardiac fatalities had evidence of both coronary heart disease and increased heart mass, and each condition was independently associated with a markedly elevated risk of cardiac death. Targeted screening for coronary heart disease, increased heart mass, and evidence of prior myocardial infarction should be considered to reduce duty-related cardiac deaths among firefighters. | en_US |
dc.format | en_US | |
dc.language.iso | en | en_US |
dc.relation.ispartof | Journal of the American Heart Association | en_US |
dc.rights | © The Authors | en_US |
dc.subject | Autopsy | en_US |
dc.subject | Cardiomegaly | en_US |
dc.subject | Coronary heart disease | en_US |
dc.subject | Firefighting | en_US |
dc.subject | Left ventricular hypertrophy | en_US |
dc.title | Pathoanatomic Findings Associated With Duty-Related Cardiac Death in US Firefighters: A Case-Control Study | en_US |
dc.type | Article | en_US |
dc.collaboration | College Saratoga Springs NY | en_US |
dc.collaboration | Cyprus University of Technology | en_US |
dc.collaboration | Harvard University | en_US |
dc.collaboration | Medical School Cambridge MA | en_US |
dc.collaboration | Medicine University of Brasilia | en_US |
dc.subject.category | Clinical Medicine | en_US |
dc.journals | Open Access | en_US |
dc.country | United States | en_US |
dc.country | Brazil | en_US |
dc.country | Cyprus | en_US |
dc.subject.field | Medical and Health Sciences | en_US |
dc.publication | Peer Reviewed | en_US |
dc.identifier.doi | 10.1161/JAHA.118.009446 | en_US |
dc.relation.issue | 18 | en_US |
dc.relation.volume | 7 | en_US |
cut.common.academicyear | 2018-2019 | en_US |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
crisitem.journal.journalissn | 2047-9980 | - |
crisitem.journal.publisher | Wiley | - |
crisitem.author.dept | Department of Rehabilitation Sciences | - |
crisitem.author.faculty | Faculty of Health Sciences | - |
crisitem.author.orcid | 0000-0003-0503-1538 | - |
crisitem.author.parentorg | Faculty of Health Sciences | - |
Εμφανίζεται στις συλλογές: | Άρθρα/Articles |
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Αρχείο | Περιγραφή | Μέγεθος | Μορφότυπος | |
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JAHA.118.009446.pdf | Fulltext | 441.33 kB | Adobe PDF | Δείτε/ Ανοίξτε |
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