Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/10508
DC FieldValueLanguage
dc.contributor.authorKaliviotis, Efstathios-
dc.contributor.authorPasias, Ioannis-
dc.contributor.authorSherwood, Joseph M.-
dc.contributor.authorBalabani, Stavroula-
dc.contributor.otherΚαλυβιώτης, Στάθης-
dc.contributor.otherΠασιάς, Ιωάννης-
dc.date.accessioned2017-11-16T08:55:36Z-
dc.date.available2017-11-16T08:55:36Z-
dc.date.issued2017-10-
dc.identifier.citationMedical Engineering and Physics, 2017, vol. 48, pp. 23-30en_US
dc.identifier.issn13504533-
dc.identifier.urihttps://hdl.handle.net/20.500.14279/10508-
dc.description.abstractRed blood cell aggregation plays a key role in microcirculatory flows, however, little is known about the transport characteristics of red blood cell aggregates in branching geometries. This work reports on the fluxes of red blood cell aggregates of various sizes in a T-shaped microchannel, aiming to clarify the effects of different flow conditions in the outlet branches of the channel. Image analysis techniques, were utilised, and moderately aggregating human red blood cell suspensions were tested in symmetric (similar to 50-50%) and asymmetric flow splits through the two outlet (daughter) branches. The results revealed that the flux decreases with aggregate size in the inlet (parent) and daughter branches, mainly due to the fact that the number of larger structures is significantly smaller than that of smaller structures. However, when the flux in the daughter branches is examined relative to the aggregate size flux in the parent branch an increase with aggregate size is observed for a range of asymmetric flow splits. This increase is attributed to size distribution and local concentration changes in the daughter branches. The results show that the flow of larger aggregates is not suppressed downstream of a bifurcation, and that blood flow is maintained, for physiological levels of red blood cell aggregation.en_US
dc.formatpdfen_US
dc.language.isoenen_US
dc.relation.ispartofMedical Engineering and Physicsen_US
dc.rights© IPEMen_US
dc.subjectBlood flowen_US
dc.subjectRed blood cell aggregate fluxen_US
dc.subjectMicro-PIVen_US
dc.subjectImage processing techniquesen_US
dc.titleRed blood cell aggregate flux in a bifurcating microchannelen_US
dc.typeArticleen_US
dc.collaborationCyprus University of Technologyen_US
dc.collaborationUniversity of Londonen_US
dc.collaborationImperial College Londonen_US
dc.subject.categoryMedical Biotechnologyen_US
dc.journalsSubscriptionen_US
dc.countryCyprusen_US
dc.countryUnited Kingdomen_US
dc.subject.fieldMedical and Health Sciencesen_US
dc.publicationPeer Revieweden_US
dc.identifier.doi10.1016/j.medengphy.2017.04.007en_US
dc.relation.volume48en_US
cut.common.academicyear2017-2018en_US
dc.identifier.spage23en_US
dc.identifier.epage30en_US
item.grantfulltextnone-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.openairetypearticle-
item.fulltextNo Fulltext-
crisitem.journal.journalissn1350-4533-
crisitem.journal.publisherElsevier-
crisitem.author.deptDepartment of Mechanical Engineering and Materials Science and Engineering-
crisitem.author.facultyFaculty of Engineering and Technology-
crisitem.author.orcid0000-0003-4149-4396-
crisitem.author.parentorgFaculty of Engineering and Technology-
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