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https://hdl.handle.net/20.500.14279/30664
Τίτλος: | In vivo brain temperature mapping using polymer optical fiber Bragg grating sensors | Συγγραφείς: | Sui, Kunyang Meneghetti, Marcello Guanghui, Li Ioannou, Andreas Abdollahian, Parinaz Kalli, Kyriacos Nielsen, Kristian Berg, Rune W Markos, Christos |
Major Field of Science: | Engineering and Technology | Field Category: | Electrical Engineering - Electronic Engineering - Information Engineering | Λέξεις-κλειδιά: | Animals;Brain;Optical Fibers;Polymers;Rats;Temperature;Thermography | Ημερομηνία Έκδοσης: | 15-Αυγ-2023 | Πηγή: | Optics Letters, 2023, vol. 48, iss. 16, pp. 4225 - 4228 | Volume: | 48 | Issue: | 16 | Start page: | 4225 | End page: | 4228 | Περιοδικό: | Optics Letters | Περίληψη: | Variation of the brain temperature is strongly affected by blood flow, oxygen supply, and neural cell metabolism. Localized monitoring of the brain temperature is one of the most effective ways to correlate brain functions and diseases such as stroke, epilepsy, and mood disorders. While polymer optical fibers (POFs) are considered ideal candidates for temperature sensing in the brain, they have never been used so far in vivo. Here, we developed for the first, to the best of our knowledge, time an implantable probe based on a microstructured polymer optical fiber Bragg grating (FBG) sensor for intracranial brain temperature mapping. The temperature at different depths of the brain (starting from the cerebral cortex) and the correlation between the brain and body core temperature of a rat were recorded with a sensitivity of 33 pm/°C and accuracy <0.2°C. Our in vivo experimental results suggest that the proposed device can achieve real-time and high-resolution local temperature measurement in the brain, as well as being integrated with existing neural interfaces. | URI: | https://hdl.handle.net/20.500.14279/30664 | ISSN: | 01469592 | DOI: | 10.1364/OL.498031 | Rights: | Attribution-NonCommercial-NoDerivatives 4.0 International | Type: | Article | Affiliation: | Technical University of Denmark University of Copenhagen Cyprus University of Technology SHUTE Sensing Solutions A/S |
Εμφανίζεται στις συλλογές: | Άρθρα/Articles |
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