Please use this identifier to cite or link to this item:
|Title:||HPLC-SPE-NMR characterization of major metabolites in Salvia fruticosa mill. Extract with antifungal potential: Relevance of carnosic acid, carnosol, and hispidulin||Authors:||Exarchou, Vassiliki
Pieters, Luc A C
|Keywords:||Aspergillus tubingensis;Botrytis cinerea;Greek sage;Penicillium digitatum;diterpenes;flavonoids;phytochemicals;q-NMR||Category:||Agricultural Biotechnology||Field:||Agricultural Sciences||Issue Date:||21-Jan-2015||Publisher:||American Chemical Society||Source:||Journal of Agricultural and Food Chemistry, Volume 63, Issue 2, 21 January 2015, Pages 457-463||DOI:||10.1021/jf5050734||Journal:||Journal of Agricultural and Food Chemistry||Abstract:||Plant pathogenic fungi are considered of significant economic importance for adversely affecting both quantitatively and qualitatively fresh and processed produce. Extracts of Salvia fruticosa were initially screened for their antifungal activity, and the ethyl acetate fraction, being the most active, was further analyzed using HPLC-SPE-NMR hyphenation. The methoxylated flavones hispidulin, salvigenin, and cirsimaritin and the diterpenes carnosic acid, carnosol, and 12-methoxycarnosic acid were identified as the major components of the extract. In addition, the concentration levels of all identified components were determined using q-NMR. The antifungal activity of the crude extract and selected phytochemicals was estimated against the fungal species Aspergillus tubingensis, Botrytis cinerea, and Penicillium digitatum. The estimated MIC and MFC values of the ethyl acetate extract of S. fruticosa, as well as three of its major constituents, carnosic acid, carnosol, and hispidulin, support their antifungal activity, especially against B. cinerea and P. digitatum, suggesting their potential use in food and agricultural systems.||URI:||http://ktisis.cut.ac.cy/handle/10488/9364||ISSN:||00218561||Rights:||© 2014 American Chemical Society.||Type:||Article|
|Appears in Collections:||Άρθρα/Articles|
Show full item record
checked on Apr 5, 2020
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.