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Title: MRI-guided focused ultrasound robotic system for the treatment of bone cancer
Authors: Menikou, Georgios 
Yiallouras, Christos 
Yiannakou, Marinos 
Damianou, Christakis A. 
Keywords: MRI;Bone;Cancer;Pain;Robot;Ultrasound
Category: Clinical Medicine
Field: Medical and Health Sciences
Issue Date: Mar-2017
Publisher: John Wiley and Sons Ltd
Source: International Journal of Medical Robotics and Computer Assisted Surgery, 2017, vol.13, no. 1
Journal: The International Journal of Medical Robotics and Computer Assisted Surgery 
Abstract: Background: A novel MRI-conditional robot was developed that navigates a focused ultrasound (FUS) transducer. With this robotic system the transducer can access bones. The intended application is pain palliation from bone cancer using thermal ablation using FUS. Methods: The robotic system has four computer-controlled axes (three linear and one angular). The robotic system was manufactured using a digital manufacturing 3D printer, using acrylonitrile butadiene styrene (ABS) plastic. MRI-conditional optical encoders were used to accurately control the robotic system. Results: The robotic system was successfully tested for MRI safety and compatibility, using fast-gradient pulse sequences and a liquid phantom. The robotic system has been tested for its functionality for creating discrete and multiple (overlapping) lesions in a gel phantom. Conclusions: An MRI-conditional FUS robotic system was developed that has the potential to create thermal lesions with the intention of treating bone cancer for the purpose of pain palliation.
ISSN: 1478-5951
DOI: 10.1002/rcs.1753
Rights: © 2016 John Wiley & Sons
Type: Article
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