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Title: Prevalence of HPV infection among Greek women attending a gynecological outpatient clinic
Authors: Stamataki, Petroula 
Papazafiropoulou, Athanasia 
Elefsiniotis, Ioannis 
Giannakopoulou, Margarita 
Brokalaki, Hero 
Apostolopoulou, Eleni 
Saroglou, George 
Sarafis, Pavlos 
Keywords: Adolescents;Alcohol consumption;Human cell;Papanicolaou test;Papillomavirus infections
Category: Health Sciences
Field: Medical and Health Sciences
Issue Date: 2010
Publisher: BioMed Central Ltd
Source: BMC Infectious diseases, 2010, Volume 10, Article number 27
Abstract: Background: Human papillomavirus (HPV) infection is a causative factor for cervical cancer. Early detection of high risk HPV types might help to identify women at high risk of cervical cancer. The aim of the present study was to examine the HPV prevalence and distribution in cervical smears in a sample of Greek women attending a gynecological outpatient clinic and to explore the determinants of the infection.Methods: A total of 225 women were studied. All women underwent a regular gynecological control. 35 HPV types were studied; 6, 11, 16, 18, 26, 31, 33, 35, 39, 40, 42, 43, 44, 45, 51, 52, 53, 54, 56, 58, 59, 61, 62, 66, 68, 70, 71, 72, 73, 81, 82, 83, 84, 85 and 89. Also, basic demographic information, sociodemographic characteristics and sexual behavior were recorded.Results: HPV was detected in 22.7% of the study population. The percentage of the newly diagnosed women with HPV infection was 17.3%. HPV-16 was the most common type detected (5.3%) followed by HPV-53 (4.9%). 66.2% of the study participants had a Pap test during the last year without any abnormalities. HPV infection was related positively with alcohol consumption (OR: 2.19, 95% CI: 1.04-4.63, P = 0.04) and number of sexual partners (OR: 2.16, 95% CI: 1.44-3.25, P < 0.001), and negatively with age (OR: 0.93, 95% CI: 0.87-0.99, P = 0.03), and monthly income (OR: 0.63, 95% CI: 0.44-0.89, P = 0.01).Conclusion: The prevalence of HPV in women attending an outpatient clinic is high. Number of sexual partners and alcohol consumption were the most significant risk factors for HPV infection, followed by young age and lower income.
ISSN: 1471-2334
DOI: 10.1186/1471-2334-10-27
Rights: © 2010 Stamataki et al
Type: Article
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