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|Title:||Thyroid disrupting chemicals in plastic additives and thyroid health||Authors:||Andra, Syam S.
Makris, Konstantinos C.
|Keywords:||Bisphenol A;Phthalates;Plastic additives;Polybrominated diphenyl ethers;Thyroid disruption;Thyroid-disrupting chemicals (TDC);Thyroid hormones;Total triiodothyronine (T3);Free triiodothyronine (FT3);Thyroxine (T4);Free thyroxine (FT4);Thyroid-stimulating hormone (TSH)||Category:||Basic Medicine||Field:||Medical and Health Sciences||Issue Date:||4-Jan-2012||Publisher:||Taylor & Francis||Source:||Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews, 2012, Volume 30, Issue 2, Pages 107-151||Abstract:||The globally escalating thyroid nodule incidence rates may be only partially ascribed to better diagnostics, allowing for the assessment of environmental risk factors on thyroid disease. Endocrine disruptors or thyroid-disrupting chemicals (TDC) like bisphenol A, phthalates, and polybrominated diphenyl ethers are widely used as plastic additives in consumer products. This comprehensive review studied the magnitude and uncertainty of TDC exposures and their effects on thyroid hormones for sensitive subpopulation groups like pregnant women, infants, and children. Our findings qualitatively suggest the mixed, significant (α = 0.05) TDC associations with natural thyroid hormones (positive or negative sign). Future studies should undertake systematic meta-analyses to elucidate pooled TDC effect estimates on thyroid health indicators and outcomes.||URI:||http://ktisis.cut.ac.cy/handle/10488/4218||ISSN:||1532-4095||DOI:||10.1080/10590501.2012.681487||Rights:||© Taylor & Francis Group||Type:||Article|
|Appears in Collections:||Άρθρα/Articles|
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