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|Title:||Ενεργοποίηση του οξυγόνου από αμφίφιλα σύμπλοκα του βαναδίου V(ΙV) και V( V) στα έλαια.||Authors:||Dieronitou, Anthi||Keywords:||olive oil oxygen activation;oxygen activation;oxygen activation;tocopheryl radicals;EPR spectroscopy;NMR spectroscopy;olive oils discrimination||Advisor:||Drouza, Chryssoula
Keramidas, Anastasios D.
|Issue Date:||25-Feb-2015||Department:||Department of Chemistry||Faculty:||Faculty of Natural Sciences||Abstract:||Oxygen can be activated in the presence of transition metals and produce reactive oxygen species. Reactive oxygen species (ROS) in low concentrations are necessary for the defence of human health against damaging agents such as bacteria and viruses. However, ROS are strong oxidative agents and large amounts of reactive oxygen species can be a weapon against the human body, because ROS can interact with biological targets such as DNA, proteins and lipids. As a result of this interaction, humans suffer from various chronic and degenerative diseases such as cancer, Parkinson, Alzheimer disease, aging and others. The human organism in order to protect itself from such diseases has developed a system that controls the balance between oxidative agents (ROS) and antioxidants (reduction molecules). One of the most important antioxidant sources is edible oils (mainly olive oils), which contain large amounts of polyphenols. Besides polyphenols, edible oils also contain lipids. Because of the edible oil’s composition, that is similar with cellular wall composition, edible oils can be used as useful biomimetic media of cellular walls. The present master thesis studies the reaction of oxygen activation which is catalyzed by amphiphilic vanadium complexes such as VOC18DEA and VOC18DPA, synthesized in the bioinorganic laboratory of Dr. Anastasios Keramidas. The study has been focused on various parameters that affect the oxygen activation in vegetable oils, such as the presence or the absence of vanadium complexes, oxygen, polyphenols, tyrosol and tocopherol. This study aims to help clarify the mechanism of cellular wall oxidation by ROS and to the characterization of vegetable oils according to their antioxidant content. In this study we used electrochemical techniques (cyclic voltammetry, linear sweep), spectroscopic techniques (EPR, NMR, UV-Vis) and analytical techniques (iodometric titration). The result from this research was that oxygen can be activated by vanadium. Also, the research shows that phenols, such as tocopherol and tyrosol, can trap the radicals that are generated from oxygen activation and that polyphenols can act as prooxidants that accelerate oxygen activation.||URI:||https://ktisis.cut.ac.cy/handle/10488/21772||Type:||MSc Thesis||Affiliation:||University of Cyprus|
|Appears in Collections:||Μεταπτυχιακές Εργασίες/ Master's thesis|
checked on Sep 21, 2021
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