Please use this identifier to cite or link to this item:
|Title:||Cancer incidence and mortality in firefighters: A state-of-the-art review and meta-analysis||Authors:||Soteriades, Elpidoforos Soterakis
Christophi, Costas A.
Kales, Stefanos N.
|Major Field of Science:||Medical and Health Sciences||Field Category:||Clinical Medicine||Keywords:||Cancer incidence;Mortality;Firefighters;Systematic review;Meta-analysis||Issue Date:||Nov-2019||Source:||Asian Pacific Journal of Cancer Prevention, 2019, vol. 20, no. 11, pp. 3221-3231||Volume:||20||Issue:||11||Start page:||3221||End page:||3231||Journal:||Asian Pacific Journal of Cancer Prevention||Abstract:||Objective: A systematic literature review and meta-analysis was conducted on the association between firefighting and cancer. Methods: A comprehensive literature search of databases including Medline, EMBASE, Biosis, NIOSHTIC2, Web of Science, Cancerlit, and HealthStar, for the period between 1966 to January 2007, was conducted. We also retrieved additional studies by manual searching. Results: A total of 49 studies were included in the meta-analysis. We found statistically significant associations between firefighting and cancers of bladder, brain and CNS, and colorectal cancers, consistent with several previous risk estimates. We also found statistically significant associations of firefighting with non-Hodgkin’s lymphoma, skin melanoma, prostate, and testicular cancer. For kidney, Hodgkin’s lymphoma, leukemia, lymphosarcoma and reticulosarcoma, multiple myeloma, and pancreatic cancer, we found some statistically significant but less consistent results. For all other cancers evaluated (esophageal, laryngeal, oral and pharyngeal, liver and gallbladder, lung, lymphatic and hematopoietic, non-melanoma skin cancer, stomach, and urinary cancer) we did not find any statistically significant associations. Conclusions: Although our meta-analysis showed statistically significant increased risks of either cancer incidence or mortality of certain cancers in association with firefighting, a number of important limitations of the underlying studies exist, which, precluded our ability to arrive at definitive conclusions regarding causation.||URI:||https://ktisis.cut.ac.cy/handle/10488/19100||ISSN:||1513-7368||DOI:||10.31557/APJCP.2019.20.11.3221||Rights:||This work is licensed under a Creative Commons AttributionNon Commercial 4.0 International License.
Attribution-NonCommercial-NoDerivatives 4.0 International
|Type:||Article||Affiliation :||United Arab Emirates University-College of Medicine and Health Sciences
Harvard T.H. Chan School of Public Health
Cyprus University of Technology
George Washington University
Cambridge Health Alliance
|Appears in Collections:||Άρθρα/Articles|
Files in This Item:
|APJCP_Volume 20_Issue 11_Pages 3221-3231.pdf||Fulltext||446.34 kB||Adobe PDF||View/Open|
|3221-3231-Elpidoforos S Soteriades-Suppl A.pdf||Supplement||306.85 kB||Adobe PDF||View/Open|
|3221-3231-Elpidoforos S Soteriades-Suppl B.pdf||Supplement||608.37 kB||Adobe PDF||View/Open|
|3221-3231-Elpidoforos S Soteriades-Suppl C.pdf||Supplement||1.23 MB||Adobe PDF||View/Open|
|3221-3231-Elpidoforos S Soteriades-Suppl D.pdf||Supplement||296.1 kB||Adobe PDF||View/Open|
checked on Jun 15, 2021
checked on Jun 17, 2021
checked on Jun 17, 2021
This item is licensed under a Creative Commons License