Please use this identifier to cite or link to this item: https://ktisis.cut.ac.cy/handle/10488/14181
Title: Application of the urban exposome framework using drinking water and quality of life indicators: a proof-of-concept study in Limassol, Cyprus
Authors: Andrianou, Xanthi D. 
Van Der Lek, Chava 
Charisiadis, Pantelis 
Ioannou, Solomon 
Fotopoulou, Kalliopi N. 
Papapanagiotou, Zoe 
Botsaris, George 
Beumer, Carijn 
Makris, Konstantinos C. 
Keywords: Epidemiology;Exposome;Small area;Urban health
Category: Health Sciences
Field: Medical and Health Sciences
Issue Date: 24-May-2019
Source: PeerJ, 2019, Volume 7, Article Number e6851
Journal: PeerJ 
Abstract: Background: Cities face rapid changes leading to increasing inequalities and emerging public health issues that require cost-effective interventions. The urban exposome concept refers to the continuous monitoring of urban environmental and health indicators using the city and smaller intra-city areas as measurement units in an interdisciplinary approach that combines qualitative and quantitative methods from social sciences, to epidemiology and exposure assessment. Methods: In this proof of concept study, drinking water and quality of life indicators were described as part of the development of the urban exposome of Limassol (Cyprus) and were combined with agnostic environment-wide association analysis. This study was conducted as a two-part project with a qualitative part assessing the perceptions of city stakeholders, and quantitative part using a cross-sectional study design (an urban population study). We mapped the water quality parameters and participant's opinions on city life (i.e., neighborhood life, health care, and green space access) using quarters (small administrative areas) as the reference unit of the city. In an exploratory, agnostic, environment-wide association study analysis, we used all variables (questionnaire responses and water quality metrics) to describe correlations between them. Results: Overall, urban drinking-water quality using conventional indicators of chemical (disinfection byproducts-trihalomethanes (THM)) and microbial (coliforms, E. coli, and Enterococci) quality did not raise particular concerns. The general health and chronic health status of the urban participants were significantly (false discovery rate corrected p-value < 0.1) associated with different health conditions such as hypertension and asthma, as well as having financial issues in access to dental care. Additionally, correlations between THM exposures and participant behavioral characteristics (e.g., household cleaning, drinking water habits) were documented. Conclusion: This proof-of-concept study showed the potential of using integrative approaches to develop urban exposomic profiles and identifying within-city differences in environmental and health indicators. The characterization of the urban exposome of Limassol will be expanded via the inclusion of biomonitoring tools and untargeted metabolomics.
URI: https://ktisis.cut.ac.cy/handle/10488/14181
ISSN: 2167-8359
31179170
DOI: 10.7717/peerj.6851
Rights: © 2019 Andrianou et al.
Type: Article
Appears in Collections:Άρθρα/Articles

Files in This Item:
File Description SizeFormat
peerj-6851.pdfFulltext5.63 MBAdobe PDFView/Open
Show full item record

Page view(s)

44
Last Week
8
Last month
checked on Aug 25, 2019

Download(s)

15
checked on Aug 25, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.