Please use this identifier to cite or link to this item: https://ktisis.cut.ac.cy/handle/10488/12594
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dc.contributor.authorPanayiotou, Andrie-
dc.contributor.authorSpaak, Jonas-
dc.contributor.authorKalani, Majid-
dc.date.accessioned2018-08-07T04:52:43Z-
dc.date.available2018-08-07T04:52:43Z-
dc.date.issued2018-07-04-
dc.identifier.citationActa Cardiologica, 2018, Volume 73, Issue 4, Pages 362-369en_US
dc.identifier.issn00015385-
dc.identifier.urihttp://ktisis.cut.ac.cy/handle/10488/12594-
dc.description.abstractBackground: Patients with kidney dysfunction are at risk of developing ischaemic heart disease. We investigated the association between eGFR and early-, mid- and long-term clinical outcome in patients undergoing coronary angiography and intervention. Methods: Retrospective study on 4968 patients with complete data on eGFR, 65% male and aged 32–80 years, admitted to Danderyd University Hospital, Stockholm, Sweden for coronary angiography and intervention from 2006 to 2008. Data were censored at 0–30 days, 31–365 days and 366–1825 days of follow-up. Results: Baseline eGFR was strongly associated with all-cause mortality at all three time periods studied with each 10 ml/min per 1.73 m2 increase in eGFR being associated with a ∼30% (p < .001), 25% (p = .002) and 20% (p < .001) decrease in all-cause mortality at 30, 365 and 1825 days respectively. Each 10 ml/min per 1.73 m2 increase in eGFR was associated with a ∼21% (p < .001) decrease in re-hospitalisation for MI at 365 days and a 6% decrease (p = .03) at day 30 for re-vascularisation. Conclusions: We report a strong association between kidney function and all-cause mortality at both early, mid- and long-term follow-up in patients undergoing coronary angiography and intervention, with eGFR significantly associated with MI-related mortality after one month of follow-up. Kidney function was also shown to be associated with risk for re-vascularisation at one month, indicating mostly procedural-related risk and with new MI at mid-term follow-up. Further research is warranted to explore the mechanisms linking kidney function and cardiovascular disease to improve both the short- and long-term care of these patients.en_US
dc.formatpdfen_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.rights© 2017 Belgian Society of Cardiologyen_US
dc.subjectEGFRen_US
dc.subjectMortalityen_US
dc.subjectMyocardial infarctionen_US
dc.subjectRevascularisationen_US
dc.titleKidney function is associated with short-term, mid-term and long-term clinical outcome after coronary angiography and interventionen_US
dc.typeArticleen_US
dc.collaborationCyprus University of Technologyen_US
dc.collaborationDanderyd University Hospitalen_US
dc.subject.categoryClinical Medicineen_US
dc.journalsSubscription Journalen_US
dc.countryCyprusen_US
dc.countrySwedenen_US
dc.subject.fieldMedical and Health Sciencesen_US
dc.publicationPeer Revieweden_US
dc.identifier.doi10.1080/00015385.2017.1395546en_US
cut.common.academicyear2017-2018en_US
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.languageiso639-1other-
crisitem.author.deptCyprus International Institute for Environmental and Public Health-
crisitem.author.facultyFaculty of Health Sciences-
crisitem.author.orcid0000-0002-6085-568X-
crisitem.author.parentorgFaculty of Health Sciences-
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