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|Title:||Cohort-friendly protocol for a sensitive and fast method for trihalomethanes in urine using gas chromatography—Triple quadrupole mass spectrometry||Authors:||Charisiadis, Pantelis
Makris, Konstantinos C.
|Keywords:||Biobanks;Biomarkers;Chlorine;Cohorts;Disinfection by products;Exposure||Category:||Basic Medicine||Field:||Medical and Health Sciences||Issue Date:||1-Jan-2018||Publisher:||Elsevier B.V.||Source:||Journal of Chromatography B, 2018, Volume 1072, Pages 336-340||DOI:||https://doi.org/10.1016/j.jchromb.2017.11.045||Abstract:||A cohort-friendly biomonitoring protocol has been developed for measuring biomarkers of exposure to disinfection by-products (trihalomethanes, THM) in urine using small initial volume (3 mL) and short analysis time (∼10 min) that facilitates the throughput of a large number of samples. The objective of this study was to optimise a cohort-friendly biomonitoring protocol for the determination of four THM analytes in human urine using gas chromatography coupled with triple quadrupole mass spectrometry (GC-QqQ-MS/MS). The proposed methodology will facilitate the inclusion of such urinary THM measurements into large population health studies.||URI:||http://ktisis.cut.ac.cy/handle/10488/10990||ISSN:||15700232||Rights:||© 2017 Elsevier B.V.||Type:||Article|
|Appears in Collections:||Άρθρα/Articles|
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