1. Ktisis Cyprus University of Technology
  2. Cyprus University of Technology (Research Output)
  3. Άρθρα/Articles
Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/30899
DC FieldValueLanguage
dc.contributor.authorAntoniou, Anastasia-
dc.contributor.authorStavrou, Marios-
dc.contributor.authorEvripidou, Nikolas-
dc.contributor.authorGeorgiou, Elena-
dc.contributor.authorKousiappa, Ioanna-
dc.contributor.authorKoupparis, Andreas-
dc.contributor.authorPapacostas, Savvas S.-
dc.contributor.authorKleopa, Kleopas A.-
dc.contributor.authorDamianou, Christakis A.-
dc.date.accessioned2023-12-05T10:50:49Z-
dc.date.available2023-12-05T10:50:49Z-
dc.date.issued2023-07-29-
dc.identifier.citationJournal of Ultrasound, 2023en_US
dc.identifier.issn19713495-
dc.identifier.urihttps://hdl.handle.net/20.500.14279/30899-
dc.description.abstractAmyloid-β (Aβ) peptides, the main component of amyloid plaques found in the Alzheimer's disease (AD) brain, are implicated in its pathogenesis, and are considered a key target in AD therapeutics. We herein propose a reliable strategy for non-invasively delivering a specific anti-Aβ antibody in a mouse model of AD by microbubbles-enhanced Focused Ultrasound (FUS)-mediated Blood-brain barrier disruption (BBBD), using a simple single stage MR-compatible positioning device.en_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Ultrasounden_US
dc.rights© The Author(s)en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAlzheimer’s diseaseen_US
dc.subjectAnti-Αβen_US
dc.subjectAntibodyen_US
dc.subjectBBBen_US
dc.subjectMiceen_US
dc.subjectUltrasounden_US
dc.titleFUS-mediated blood-brain barrier disruption for delivering anti-Aβ antibodies in 5XFAD Alzheimer's disease miceen_US
dc.typeArticleen_US
dc.collaborationCyprus University of Technologyen_US
dc.collaborationCyprus Institute of Neurology and Geneticsen_US
dc.subject.categoryHealth Sciencesen_US
dc.journalsSubscriptionen_US
dc.countryCyprusen_US
dc.subject.fieldMedical and Health Sciencesen_US
dc.publicationPeer Revieweden_US
dc.identifier.doi10.1007/s40477-023-00805-4en_US
dc.identifier.pmid37516718-
dc.identifier.scopus2-s2.0-85166255451-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85166255451-
cut.common.academicyear2022-2023en_US
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.openairetypearticle-
item.languageiso639-1en-
crisitem.journal.journalissn1876-7931-
crisitem.journal.publisherSpringer Nature-
crisitem.author.deptDepartment of Electrical Engineering, Computer Engineering and Informatics-
crisitem.author.facultyFaculty of Engineering and Technology-
crisitem.author.orcid0000-0003-0424-2851-
crisitem.author.parentorgFaculty of Engineering and Technology-
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