1. Ktisis Cyprus University of Technology
  2. Cyprus University of Technology (Research Output)
  3. Άρθρα/Articles
Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14279/27521
Title: Enzymatic transformation of flavonoids and terpenoids: Structural and functional diversity of the novel derivatives
Authors: Xanthakis, Epameinondas 
Theodosiou, Eleni 
Magkouta, Sophia 
Stamatis, Haralambos 
Loutrari, Heleni 
Roussos, Charis 
Kolisis, Fragiskos N. 
Major Field of Science: Engineering and Technology
Field Category: Other Engineering and Technologies
Keywords: Anti-tumor activity;Biocatalysis;Flavonoids;Phytochemicals;Terpenoids
Issue Date: 3-Jan-2010
Source: Pure and Applied Chemistry, vol. 82, no. 1, pp. 1–16
Volume: 82
Issue: 1
Start page: 1
End page: 16
Journal: Pure and Applied Chemistry 
Abstract: Flavonoids and terpenoids are promising candidates for use as functional foods and novel therapeutics due to their prominent biological activities. However, the use of several bioactive plant compounds is limited by low stability and solubility problems. This review underlines the feasibility of enzymatic synthesis of novel bioactive analogs of selected flavonoids (silybin, rutin) and terpenoids (perillyl alcohol, POH) in nonconventional reaction systems. The effect of various parameters on the enzymatic acylation and/or glucosylation of these phytochemicals was studied. Also, the role of the structure of the novel molecules in relation to their biological function was investigated in various cancer cell lines.
URI: https://hdl.handle.net/20.500.14279/27521
ISSN: 13653075
DOI: 10.1351/PAC-CON-09-01-19
Rights: © IUPAC
Type: Article
Affiliation : National Technical University Of Athens 
University of Ioannina 
University of Athens 
Appears in Collections:Άρθρα/Articles

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