Please use this identifier to cite or link to this item: http://ktisis.cut.ac.cy/handle/10488/9211
Title: Effect of Body Mass Index on Left Ventricular Mass in Career Male Firefighters
Authors: Korre, Maria 
Porto, Luiz Guilherme Grossi 
Farioli, Andrea 
Yang, Justin 
Christiani, David C. 
Christophi, Costas A. 
Lombardi, David A. 
Kovacs, Richard J. 
Mastouri, Ronald 
Abbasi, Siddique A. 
Steigner, Michael L. 
Moffatt, Steven 
Smith, Denise Louise 
Kales, Stefanos N. 
Keywords: Left ventricular mass
Cardiovascular disease
Cardiac death
Issue Date: 1-Dec-2016
Publisher: Elsevier Inc.
Source: American Journal of Cardiology, 2016, Volume 118, Issue 11, Pages 1769-1773
Abstract: Left ventricular (LV) mass is a strong predictor of cardiovascular disease (CVD) events; increased LV mass is common among US firefighters and plays a major role in firefighter sudden cardiac death. We aim to identify significant predictors of LV mass among firefighters. Cross-sectional study of 400 career male firefighters selected by an enriched randomization strategy. Weighted analyses were performed based on the total number of risk factors per subject with inverse probability weighting. LV mass was assessed by echocardiography (ECHO) and cardiac magnetic resonance, and normalized (indexed) for height. CVD risk parameters included vital signs at rest, body mass index (BMI)–defined obesity, obstructive sleep apnea risk, low cardiorespiratory fitness, and physical activity. Linear regression models were performed. In multivariate analyses, BMI was the only consistent significant independent predictor of LV mass indexes (all, p <0.001). A 1-unit decrease in BMI was associated with 1-unit (g/m1.7) reduction of LV mass/height1.7 after adjustment for age, obstructive sleep apnea risk, and cardiorespiratory fitness. In conclusion, after height-indexing ECHO-measured and cardiac magnetic resonance–measured LV mass, BMI was found to be a major driver of LV mass among firefighters. Our findings taken together with previous research suggest that reducing obesity will improve CVD risk profiles and decrease on-duty CVD and sudden cardiac death events in the fire service. Our results may also support targeted noninvasive screening for LV hypertrophy with ECHO among obese firefighters.
URI: http://ktisis.cut.ac.cy/handle/10488/9211
ISSN: 00029149
Rights: © 2016 The Authors
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