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|Title:||Shear-reducing insoles to prevent foot ulceration in high-risk diabetic patients||Authors:||Constantinides, Georgios
Lavery, Lawrence A.
|Keywords:||Diabetic neuropathies;Foot--Ulcers;Patients||Category:||Medical Engineering||Field:||Engineering and Technology||Issue Date:||2012||Publisher:||Lippincott Williams & Wilkins||Source:||Advances in Skin and Wound Care, 2012, Volume 25, Issue 11, Pages 519-524||Abstract:||OBJECTIVE: The objective of this study was to evaluate the effectiveness of a shear-reducing insole compared with a standard insole design to prevent foot ulceration in high-risk patients with diabetes. RESEARCH DESIGN AND METHODS: A total of 299 patients with diabetic neuropathy and loss of protective sensation, foot deformity, or history of foot ulceration were randomized into a standard therapy group (n = 150) or a shear-reducing insole group (n = 149). Patients were evaluated for 18 months. Standard therapy group consisted of therapeutic footwear, diabetic foot education, and regular foot evaluation by a podiatrist. The shear-reducing insole group included a novel insole designed to reduce both pressure and shear on the sole of the foot. Insoles were replaced every 4 months in both groups. The primary clinical outcome was foot ulceration. The authors used Cox proportional hazards regression to evaluate time to ulceration. RESULTS: There were 2 significant factors from the Cox regression model: insole treatment and history of a foot complication. The standard therapy group was about 3.5 times more likely to develop an ulcer compared with shear-reducing insole group (hazard ratio, 3.47; 95% confidence interval, 0.96-12.67). CONCLUSIONS: These results suggest that a shear-reducing insole is more effective than traditional insoles to prevent foot ulcers in high-risk persons with diabetes.||URI:||http://ktisis.cut.ac.cy/handle/10488/7742||ISSN:||15277941||DOI:||10.1097/01.ASW.0000422625.17407.93||Rights:||© 2012 Lippincott Williams & Wilkins, Inc||Type:||Article|
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