Please use this identifier to cite or link to this item:
Title: Numerical and experimental study of a novel phase contrast magnetic resonance (PC-MR) imaging technique: Sparse Interleaved Referencing PC-MR imaging
Authors: Li, Longchuan 
Doyle, Mark W. 
Anayiotos, Andreas 
Keywords: Heart Imaging;Image analysis;Apparitions
Issue Date: 2008
Publisher: John Wiley & Sons
Source: Journal of Magnetic Resonance Imaging, 2008, Volume 27, Issue 4, Pages 898-907
Abstract: Purpose: To use numerical simulation and experimental approaches to introduce a novel phase contrast magnetic resonance (PC-MR) data processing technique termed Sparse Interleaved Referencing PC-MR, with potential to improve accuracy, temporal resolution, and signal-to-noise ratio (SNR) of PC-MR data. Materials and Methods: Computational fluid dynamics data were generated for a two-chamber orifice flow model simulating valvular regurgitation. The numerical results were validated and used to simulate conventional and Sparse Interleaved Referencing PC-MR data acquisitions. Common data sets were processed using conventional and Sparse Interleaved Referencing approaches and quantitative errors in velocity-time waveforms were measured and compared. In vitro phantom jet flow data and in vivo ascending aorta data were acquired and used to simulate Sparse Interleaved Referencing PC-MR. Results: The Sparse Interleaved Referencing PC-MR data showed significantly better representation of the velocity-time waveform in three areas: (i) lower root-mean-square errors (9.0 ± 1.0% versus 24.0 ± 0.2%; P < 0.005), (ii) simulation of conventionally processed data showed a pattern of peak velocity overestimation, which was experimentally demonstrated in in vitro data, whereas overestimation of peak velocity was dramatically attenuated using Sparse Interleaved Referencing (2.8 ± 0.4% versus 16.9 ± 6.4%, P < 0.005), and (iii) compared with the conventional scan, an average of 119.4 ± 26.6% (P < 0.005) SNR was realized in in vitro and in vivo Sparse Interleaved Referencing PC-MR data. Conclusion: Simulation and in vitro/in vivo results show that Sparse Interleaved Referencing PC-MR processed data in pulsatile and jet flow showed higher accuracy, better peak velocity representation, and improved SNR compared with the data processed using the conventional PC-MR method.
ISSN: 10531807
DOI: 10.1002/jmri.21323
Rights: © 2008 Wiley-Liss, Inc
Type: Article
Appears in Collections:Άρθρα/Articles

Show full item record

Page view(s)

Last Week
Last month
checked on Dec 14, 2018

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.