Please use this identifier to cite or link to this item: http://ktisis.cut.ac.cy/handle/10488/7506
Title: Effect of head posture on the healthy human carotid bifurcation hemodynamics
Authors: Aristokleous, Nicolas 
Khozeymeh, Mohammad Iman 
Anayiotos, Andreas 
Keywords: Atherosclerosis
Geometry
Hemodynamics
Carotid artery
Issue Date: 2012
Publisher: Springer
Source: Medical and Biological Engineering and Computing, 2012, Pages 1-12
Abstract: Head and neck postures may cause morphology changes to the geometry of the carotid bifurcation (CB) that alter the low and oscillating wall shear stress (WSS) regions previously reported as important in the development of atherosclerosis. Here the right and left CB were imaged by MRI in two healthy subjects in the neutral head posture with the subject in the supine position and in two other head postures with the subject in the prone position: (1) rightward rotation up to 80°, and (2) leftward rotation up to 80°. Image-based computational models were constructed to investigate the effect of posture on arterial geometry and local hemodynamics. The area exposure to unfavorable hemodynamics, based on thresholds set for oscillatory shear index (OSI), WSS and relative residence time, was used to quantify the hemodynamic impact on the wall. Torsion of the head was found to: (1) cause notable changes in the bifurcation and internal carotid artery angles and, in most cases, on cross-sectional area ratios for common, internal and external carotid artery, (2) change the spatial distribution of wall regions exposed to unfavorable hemodynamics, and (3) cause a marked change in the hemodynamic burden on the wall when the OSI was considered. These findings suggest that head posture may be associated with the genesis and development of atherosclerotic disease as well as complications in stenotic and stented vessels.
URI: http://ktisis.cut.ac.cy/handle/10488/7506
ISSN: 01400118
DOI: 10.1007/s11517-012-0985-6
Rights: © International Federation for Medical and Biological Engineering 2012
Appears in Collections:Άρθρα/Articles

Show full item record

SCOPUSTM   
Citations 20

6
checked on Feb 21, 2017

WEB OF SCIENCETM
Citations 50

3
checked on Dec 5, 2016

Page view(s)

1
checked on Jan 29, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.