Please use this identifier to cite or link to this item: http://ktisis.cut.ac.cy/handle/10488/7347
Title: Retinal flow cytometer
Authors: Alt, Clemens 
Veilleux, Israel
Pitsillides, Costas 
Keywords: Flow cytometry;Optical instruments;Cells;Real-time control;Mice;Lymphocytes
Issue Date: 2007
Publisher: The Optical Society
Source: Optics letters, 2007, Volume 32, Issue 23, Pages 3450-3452
Abstract: The in vivo flow cytometer is an instrument capable of continuous, real-time monitoring of fluorescently labeled cells in the circulation without the need to draw blood samples. However, the original system probes a single vessel in the mouse ear; the small sample volume limits the sensitivity of the technique. We describe an in vivo retinal flow cytometer that simultaneously probes five artery–vein pairs in the mouse eye by circularly scanning a small laser spot rapidly around the optic nerve head. We demonstrate that the retinal flow cytometer detects about five times more cells per minute than the original in vivo flow cytometer does in the ear
URI: http://ktisis.cut.ac.cy/handle/10488/7347
ISSN: 0146-9592 (print)
1539-4794 (online)
DOI: 10.1364/OL.32.003450
Rights: © 2007 Optical Society of America
Type: Article
Appears in Collections:Άρθρα/Articles

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