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Title: The contemporary use of electron microscopy in the diagnosis of ciliary disorders and sperm centriolar abnormalities
Authors: Yiallouros, Panayiotis K. 
Nearchou, Marianna 
Hadjisavvas, Andreas 
Kyriacou, Kyriacos C. 
Keywords: Centriolar sperm abnormalities
Ciliopathies and PCD, phenotypic/genetic disorders
Ciliopathies, heterogeneous group of disorders in PCD
EM, for ciliary disorders/sperm centriolar abnormalities
Frequent abnormalities, absence/shortening of ODAs/IDAs
Major genes implicated in PCD, in humans
Motile cilia ultrastructure, TEM in diagnosis
PCD diagnosis, challenging, requiring clinical work-up; PCD genetics, autosomal recessive disorder
PCD, and ultrastructural changes
Issue Date: 2012
Publisher: John Wiley and Sons
Source: Diagnostic Electron Microscopy: A Practical Guide to Tissue Preparation and Interpretation, Pages 221-236
Abstract: Cilia and flagella are hair-like structures which extend from the cell membrane and are involved in a variety of biological functions in eukaryotes. Cilia are found in a wide range of human tissues and cell types including: the epithelium of the upper and lower respiratory tracts, the epithelium of the kidney, bile and pancreatic ducts, the embryonic node, and the ependymal cells in the brain and in the oviduct epithelium.
ISBN: 978-1-119-97399-7
DOI: 10.1002/9781118452813.ch7
Appears in Collections:Κεφάλαια βιβλίων/Book chapters

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